Cargando…

Complex Systems Biology Approach in Connecting PI3K-Akt and NF-κB Pathways in Prostate Cancer

Phosphatidylinositol 3′-OH kinase (PI3K)-Akt and transcription factor NF-κB are important molecules involved in the regulation of cell proliferation, apoptosis, and oncogenesis. Both PI3K-Akt and Nuclear Factor-kappaB (NF-κB) are involved in the development and progression of prostate cancer, howeve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shankar, Eswar, Weis, Michael C., Avva, Jayant, Shukla, Sanjeev, Shukla, Meenakshi, Sreenath, Sree N., Gupta, Sanjay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468646/ https://www.ncbi.nlm.nih.gov/pubmed/30813597 http://dx.doi.org/10.3390/cells8030201

Ejemplares similares

Suppression of NF-κB and NF-κB-Regulated Gene Expression by Apigenin through IκBα and IKK Pathway in TRAMP Mice
por: Shukla, Sanjeev, et al.
Publicado: (2015)

A Data-Driven, Mathematical Model of Mammalian Cell Cycle Regulation
por: Weis, Michael C., et al.
Publicado: (2014)

Dynamic Epitope Expression from Static Cytometry Data: Principles and Reproducibility
por: Jacobberger, James W., et al.
Publicado: (2012)

Dynamic Expression Profiles from Static Cytometry Data: Component Fitting and Conversion to Relative, “Same Scale” Values
por: Avva, Jayant, et al.
Publicado: (2012)

Betulinic Acid-Mediated Apoptosis in Human Prostate Cancer Cells Involves p53 and Nuclear Factor-Kappa B (NF-κB) Pathways
por: Shankar, Eswar, et al.
Publicado: (2017)

Apigenin blocks IKKα activation and suppresses prostate cancer progression
por: Shukla, Sanjeev, et al.
Publicado: (2015)

Targeting the PI3K/AKT/mTOR/NFκB Axis in Ovarian Cancer
por: Ghoneum, Alia, et al.
Publicado: (2020)

Isorhamnetin Induces Melanoma Cell Apoptosis via the PI3K/Akt and NF-κB Pathways
por: Duan, Ran, et al.
Publicado: (2020)

Hierarchical clustering of immunohistochemical analysis of the activated ErbB/PI3K/Akt/NF-κB signalling pathway and prognostic significance in prostate cancer
por: Koumakpayi, I H, et al.
Publicado: (2010)

Evodiamine as the Active Compound of Evodiae fructus to Inhibit Proliferation and Migration of Prostate Cancer through PI3K/AKT/NF-κB Signaling Pathway
por: Lei, Yuhe, et al.
Publicado: (2022)

PI3K-AKT-mTOR and NFκB Pathways in Ovarian Cancer: Implications for Targeted Therapeutics
por: Ghoneum, Alia, et al.
Publicado: (2019)

PLCA8 suppresses breast cancer apoptosis by activating the PI3k/AKT/NF‐κB pathway
por: Mao, Misha, et al.
Publicado: (2019)

Oxidative Stress and Antioxidant Status in High-Risk Prostate Cancer Subjects
por: Shukla, Sanjeev, et al.
Publicado: (2020)

VEGF is upregulated by hypoxia-induced mitogenic factor via the PI-3K/Akt-NF-κB signaling pathway
por: Tong, Qiangsong, et al.
Publicado: (2006)

Dynamic Motile T Cells Highly Respond to the T Cell Stimulation via PI3K-Akt and NF-κB Pathways
por: Kim, Hye-Ran, et al.
Publicado: (2013)

Garlic Oil Suppressed Nitrosodiethylamine-Induced Hepatocarcinoma in Rats by Inhibiting PI3K-AKT-NF-κB Pathway
por: Zhang, Cui-Li, et al.
Publicado: (2015)

Effect of Compound Chuanxiong Capsule on Inflammatory Reaction and PI3K/Akt/NF-κB Signaling Pathway in Atherosclerosis
por: Kang, Qunfu, et al.
Publicado: (2015)

Effects of vaspin on pancreatic β cell secretion via PI3K/Akt and NF-κB signaling pathways
por: Liu, Shiwei, et al.
Publicado: (2017)

Dihydroartemisinin attenuates autoimmune thyroiditis by inhibiting the CXCR3/PI3K/AKT/NF-κB signaling pathway
por: Liu, Huijuan, et al.
Publicado: (2017)

Arctigenin prevents the progression of osteoarthritis by targeting PI3K/Akt/NF‐κB axis: In vitro and in vivo studies
por: Tang, Shangkun, et al.
Publicado: (2020)

Critical roles of PI3K/Akt/NF-κB survival axis in angiotensin II-induced podocyte injury
por: Wang, Junjie, et al.
Publicado: (2019)

Maltol prevents the progression of osteoarthritis by targeting PI3K/Akt/NF‐κB pathway: In vitro and in vivo studies
por: Lu, Hongwei, et al.
Publicado: (2020)

Dihydroartemisinin Attenuated Intervertebral Disc Degeneration via Inhibiting PI3K/AKT and NF-κB Signaling Pathways
por: Liao, Zhiheng, et al.
Publicado: (2022)

Flotillin-2 promotes metastasis of nasopharyngeal carcinoma by activating NF-κB and PI3K/Akt3 signaling pathways
por: Liu, Jie, et al.
Publicado: (2015)

Irisin Enhances Doxorubicin-Induced Cell Apoptosis in Pancreatic Cancer by Inhibiting the PI3K/AKT/NF-κB Pathway
por: Liu, Jiayu, et al.
Publicado: (2019)

Cajanol Sensitizes A2780/Taxol Cells to Paclitaxel by Inhibiting the PI3K/Akt/NF-κB Signaling Pathway
por: Sui, Ming, et al.
Publicado: (2021)

SHIP1 Activator AQX-1125 Regulates Osteogenesis and Osteoclastogenesis Through PI3K/Akt and NF-κb Signaling
por: Xie, Xudong, et al.
Publicado: (2022)

UBAP2L promotes gastric cancer metastasis by activating NF-κB through PI3K/AKT pathway
por: Li, Ou, et al.
Publicado: (2022)

Renshen Baidu powder protects ulcerative colitis via inhibiting the PI3K/Akt/NF-κB signaling pathway
por: Ye, Zhen, et al.
Publicado: (2022)

Compound C Inhibits Ovarian Cancer Progression via PI3K-AKT-mTOR-NFκB Pathway
por: Ghoneum, Alia, et al.
Publicado: (2022)

FAM83B promotes the invasion of primary lung adenocarcinoma via PI3K/AKT/NF-κB pathway
por: Zhang, Jing, et al.
Publicado: (2023)

Atractylenolide III ameliorated reflux esophagitis via PI3K/AKT/NF-κB/iNOS pathway in rats
por: Si, Xianzhe, et al.
Publicado: (2023)

Phyllanthus Suppresses Prostate Cancer Cell, PC-3, Proliferation and Induces Apoptosis through Multiple Signalling Pathways (MAPKs, PI3K/Akt, NFκB, and Hypoxia)
por: Tang, Yin-Quan, et al.
Publicado: (2013)

Mycobacterial Heparin-binding Hemagglutinin Antigen Activates Inflammatory Responses through PI3-K/Akt, NF-κB, and MAPK Pathways
por: Kim, Ki-Hye, et al.
Publicado: (2011)

LFG-500 Inhibits the Invasion of Cancer Cells via Down-Regulation of PI3K/AKT/NF-κB Signaling Pathway
por: Li, Chenglin, et al.
Publicado: (2014)

Si-Wu-tang extract stimulates bone formation through PI3K/Akt/NF-κB signaling pathways in osteoblasts
por: Wu, Chi-Ming, et al.
Publicado: (2013)

Resveratrol Inhibits the Invasion of Glioblastoma-Initiating Cells via Down-Regulation of the PI3K/Akt/NF-κB Signaling Pathway
por: Jiao, Yuming, et al.
Publicado: (2015)

Down-regulation of ABCE1 inhibits temozolomide resistance in glioma through the PI3K/Akt/NF-κB signaling pathway
por: Zhang, Peng, et al.
Publicado: (2018)

ERCC6L promotes the progression of hepatocellular carcinoma through activating PI3K/AKT and NF-κB signaling pathway
por: Chen, Han, et al.
Publicado: (2020)

A Discovery of Clinically Approved Formula FBRP for Repositioning to Treat HCC by Inhibiting PI3K/AKT/NF-κB Activation
por: Zhang, Yanqiong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_lu6pahol4os65gveif5hp639c8