Acquired Resistance to Antibody-Drug Conjugates

Antibody-drug conjugates (ADCs) combine the tumor selectivity of antibodies with the potency of cytotoxic small molecules thereby constituting antibody-mediated chemotherapy. As this inherently limits the adverse effects of the chemotherapeutic, such approaches are heavily pursued by pharma and biot...

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Detalles Bibliográficos
Autores principales: Collins, Denis M., Bossenmaier, Birgit, Kollmorgen, Gwendlyn, Niederfellner, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468698/
https://www.ncbi.nlm.nih.gov/pubmed/30897808
http://dx.doi.org/10.3390/cancers11030394

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