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Anti-infective efficacy of Psidium guajava L. leaves against certain pathogenic bacteria
Water extracts of Psidium guajava leaves prepared by three different extraction methods were compared with respect to their anti-infective activity against Pseudomonas aeruginosa and Staphylococcus aureus in the nematode host Caenorhabditis elegans. The water extract prepared by Microwave Assisted E...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468707/ https://www.ncbi.nlm.nih.gov/pubmed/31031967 http://dx.doi.org/10.12688/f1000research.17500.2 |
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author | Patel, Pooja Joshi, Chinmayi Birdi, Tannaz Kothari, Vijay |
author_facet | Patel, Pooja Joshi, Chinmayi Birdi, Tannaz Kothari, Vijay |
author_sort | Patel, Pooja |
collection | PubMed |
description | Water extracts of Psidium guajava leaves prepared by three different extraction methods were compared with respect to their anti-infective activity against Pseudomonas aeruginosa and Staphylococcus aureus in the nematode host Caenorhabditis elegans. The water extract prepared by Microwave Assisted Extraction method was found to have better anti-infective activity, and its activity was further compared with hydroalcoholic extract prepared using the same extraction method against five different pathogenic bacteria. Both these extracts could attenuate virulence of P. aeruginosa, S. aureus, Serratia marcescens, and Chromobacterium violaceum, towards C. elegans. Anti-infective efficacy of P. guajava leaf extract seems partly to stem from its quorum-modulatory property, as it could modulate production of quorum sensing-regulated pigments in all the susceptible bacteria. |
format | Online Article Text |
id | pubmed-6468707 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | F1000 Research Limited |
record_format | MEDLINE/PubMed |
spelling | pubmed-64687072019-04-25 Anti-infective efficacy of Psidium guajava L. leaves against certain pathogenic bacteria Patel, Pooja Joshi, Chinmayi Birdi, Tannaz Kothari, Vijay F1000Res Research Note Water extracts of Psidium guajava leaves prepared by three different extraction methods were compared with respect to their anti-infective activity against Pseudomonas aeruginosa and Staphylococcus aureus in the nematode host Caenorhabditis elegans. The water extract prepared by Microwave Assisted Extraction method was found to have better anti-infective activity, and its activity was further compared with hydroalcoholic extract prepared using the same extraction method against five different pathogenic bacteria. Both these extracts could attenuate virulence of P. aeruginosa, S. aureus, Serratia marcescens, and Chromobacterium violaceum, towards C. elegans. Anti-infective efficacy of P. guajava leaf extract seems partly to stem from its quorum-modulatory property, as it could modulate production of quorum sensing-regulated pigments in all the susceptible bacteria. F1000 Research Limited 2019-03-25 /pmc/articles/PMC6468707/ /pubmed/31031967 http://dx.doi.org/10.12688/f1000research.17500.2 Text en Copyright: © 2019 Patel P et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Note Patel, Pooja Joshi, Chinmayi Birdi, Tannaz Kothari, Vijay Anti-infective efficacy of Psidium guajava L. leaves against certain pathogenic bacteria |
title | Anti-infective efficacy of
Psidium guajava L. leaves against certain pathogenic bacteria |
title_full | Anti-infective efficacy of
Psidium guajava L. leaves against certain pathogenic bacteria |
title_fullStr | Anti-infective efficacy of
Psidium guajava L. leaves against certain pathogenic bacteria |
title_full_unstemmed | Anti-infective efficacy of
Psidium guajava L. leaves against certain pathogenic bacteria |
title_short | Anti-infective efficacy of
Psidium guajava L. leaves against certain pathogenic bacteria |
title_sort | anti-infective efficacy of
psidium guajava l. leaves against certain pathogenic bacteria |
topic | Research Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468707/ https://www.ncbi.nlm.nih.gov/pubmed/31031967 http://dx.doi.org/10.12688/f1000research.17500.2 |
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