Targeting the Post-Irradiation Tumor Microenvironment in Glioblastoma via Inhibition of CXCL12

Radiotherapy is a mainstay in glioblastoma therapy as it not only directly targets tumor cells but also depletes the tumor microvasculature. The resulting intra-tumoral hypoxia initiates a chain of events that ultimately leads to re-vascularization, immunosuppression and, ultimately, tumor-regrowth....

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Detalles Bibliográficos
Autores principales: Giordano, Frank A., Link, Barbara, Glas, Martin, Herrlinger, Ulrich, Wenz, Frederik, Umansky, Viktor, Brown, J. Martin, Herskind, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468743/
https://www.ncbi.nlm.nih.gov/pubmed/30813533
http://dx.doi.org/10.3390/cancers11030272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468743/
https://www.ncbi.nlm.nih.gov/pubmed/30813533
http://dx.doi.org/10.3390/cancers11030272

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