Cargando…

Niclosamide Triggers Non-Canonical LC3 Lipidation

Autophagy is a highly- evolutionarily-conserved catabolic pathway activated by various cellular stresses. Recently, non-canonical autophagy (NCA), which does not require all of the ATG proteins to form autophagosome or autophagosome-like structures, has been found in various conditions. Moreover, mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yajun, Luo, Xia, Shan, Hao, Fu, Yuanyuan, Gu, Qianqian, Zheng, Xueping, Dai, Qi, Xia, Fan, Zheng, Zhihua, Liu, Peiqing, Yin, Xiao-Ming, Hong, Liang, Li, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468753/ https://www.ncbi.nlm.nih.gov/pubmed/30875964 http://dx.doi.org/10.3390/cells8030248

Ejemplares similares

Golgi-associated LC3 lipidation requires V-ATPase in noncanonical autophagy
por: Gao, Ying, et al.
Publicado: (2016)

A one-step specific assay for continuous detection of sirtuin 2 activity
por: Dai, Qi, et al.
Publicado: (2019)

Niclosamide inhibition of STAT3 synergizes with erlotinib in human colon cancer
por: Shi, Lingyi, et al.
Publicado: (2017)

Repurposing Niclosamide for Targeting Pancreatic Cancer by Inhibiting Hh/Gli Non-Canonical Axis of Gsk3β
por: Kaushal, Jyoti B., et al.
Publicado: (2021)

The magic bullet: Niclosamide
por: Jiang, Haowen, et al.
Publicado: (2022)

Antitumor effect and metabonomics of niclosamide micelles
por: Hang, Jiarong, et al.
Publicado: (2022)

Niclosamide: Beyond an antihelminthic drug
por: Chen, Wei, et al.
Publicado: (2018)

Antihelminthic niclosamide modulates dendritic cells activation and function
por: Wu, Chieh-Shan, et al.
Publicado: (2014)

Migration and Transformation Characteristics of Niclosamide in a Soil–Plant System
por: Luo, Cui, et al.
Publicado: (2018)

Binding interactions of niclosamide with serum proteins
por: Maltas, Esra
Publicado: (2014)

Niclosamide for Covid-19: bridging the gap
por: Al-kuraishy, Hayder M., et al.
Publicado: (2021)

Synthesis and biological evaluation of niclosamide PROTACs
por: Munoz, Erick, et al.
Publicado: (2022)

Repurposing niclosamide for the treatment of neurological disorders
por: Apolloni, Savina, et al.
Publicado: (2023)

Desolvation Processes in Channel Solvates of Niclosamide
por: Mann, Jen E., et al.
Publicado: (2023)

Study on the Synergistic Molluscicidal Effect of Pedunsaponin A and Niclosamide
por: Yang, Chunping, et al.
Publicado: (2022)

Niclosamide Blocks Rice Leaf Blight by Inhibiting Biofilm Formation of Xanthomonas oryzae
por: Sahu, Sunil Kumar, et al.
Publicado: (2018)

Niclosamide attenuates inflammatory cytokines via the autophagy pathway leading to improved outcomes in renal ischemia/reperfusion injury
por: Zhang, Lin-Xia, et al.
Publicado: (2017)

Niclosamide Is Active In Vitro against Mycetoma Pathogens
por: Mahmoud, Abdelhalim B., et al.
Publicado: (2021)

Niclosamide—A promising treatment for COVID‐19
por: Singh, Shivani, et al.
Publicado: (2022)

Sensitivity of Oncomelania hupensis to Niclosamide: A Nation-Wide Survey in China
por: Dai, Jianrong, et al.
Publicado: (2014)

The Simultaneous Inhibitory Effect of Niclosamide on RANKL-Induced Osteoclast Formation and Osteoblast Differentiation
por: Liu, Fei-Lan, et al.
Publicado: (2017)

Antiviral activities of niclosamide and nitazoxanide against chikungunya virus entry and transmission
por: Wang, Yu-Ming, et al.
Publicado: (2016)

Combined effects of niclosamide and temozolomide against human glioblastoma tumorspheres
por: Oh, Hyeong-Cheol, et al.
Publicado: (2020)

Niclosamide inhibits ovarian carcinoma growth by interrupting cellular bioenergetics
por: Shangguan, Fugen, et al.
Publicado: (2020)

Niclosamide sensitizes nasopharyngeal carcinoma to radiation by downregulating Ku70/80 expression
por: Li, Jingjing, et al.
Publicado: (2018)

Niclosamide as a chemical probe for analyzing SARS-CoV-2 modulation of host cell lipid metabolism
por: Garrett, Timothy J., et al.
Publicado: (2023)

The WD40 domain of ATG16L1 is required for its non‐canonical role in lipidation of LC3 at single membranes
por: Fletcher, Katherine, et al.
Publicado: (2018)

Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation
por: Ulferts, Rachel, et al.
Publicado: (2021)

Niclosamide as a Promising Therapeutic Player in Human Cancer and Other Diseases
por: Wang, Zhan, et al.
Publicado: (2022)

The Anthelmintic Drug Niclosamide Induces Apoptosis, Impairs Metastasis and Reduces Immunosuppressive Cells in Breast Cancer Model
por: Ye, Tinghong, et al.
Publicado: (2014)

Repurposing the anthelmintic drug niclosamide to combat Helicobacter pylori
por: Tharmalingam, Nagendran, et al.
Publicado: (2018)

Niclosamide encapsulated polymeric nanocarriers for targeted cancer therapy
por: Jain, Nishant Kumar, et al.
Publicado: (2019)

Niclosamide potentiates TMEM16A and induces vasoconstriction
por: Liang, Pengfei, et al.
Publicado: (2023)

Niclosamide suppresses Hepatoma cell proliferation via the Wnt pathway
por: Tomizawa, Minoru, et al.
Publicado: (2013)

Niclosamide inhibits leaf blight caused by Xanthomonas oryzae in rice
por: Kim, Sung-Il, et al.
Publicado: (2016)

Drug Repurposing of the Anthelmintic Niclosamide to Treat Multidrug-Resistant Leukemia
por: Hamdoun, Sami, et al.
Publicado: (2017)

Preclinical evaluation of a nanoformulated antihelminthic, niclosamide, in ovarian cancer
por: Lin, Chi-Kang, et al.
Publicado: (2016)

Novel Antiviral Activities of Obatoclax, Emetine, Niclosamide, Brequinar, and Homoharringtonine
por: Andersen, Petter I., et al.
Publicado: (2019)

Plausible mechanisms of Niclosamide as an antiviral agent against COVID-19
por: Pindiprolu, Sai Kiran S.S., et al.
Publicado: (2020)

Investigation of niclosamide as a repurposing agent for skeletal muscle atrophy
por: Kim, Hyun-Jun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7i5mg8d3oi4c9l0f71i6c12eei