(18)F-FDG PET/CT Findings in Cytomegalovirus Colitis

We present a case demonstrating the diagnostic work-up of a patient undergoing azathioprine treatment for inflammatory bowel disease (IBD), diagnosed with an acute cytomegalovirus (CMV) infection and CMV colitis. An (18)F-FDG positron emission tomography/computed tomography (PET/CT) performed 2 week...

Descripción completa

Detalles Bibliográficos
Autores principales: Kjaer, Anna Sophie L., Ribberholt, Iben, Thomsen, Kim, Ibsen, Per H., Markova, Elena, Graff, Jesper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Interesting Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468765/
https://www.ncbi.nlm.nih.gov/pubmed/30587768
http://dx.doi.org/10.3390/diagnostics9010003
Descripción
Sumario:We present a case demonstrating the diagnostic work-up of a patient undergoing azathioprine treatment for inflammatory bowel disease (IBD), diagnosed with an acute cytomegalovirus (CMV) infection and CMV colitis. An (18)F-FDG positron emission tomography/computed tomography (PET/CT) performed 2 weeks after debut of symptoms revealed pathological (18)F-FDG uptake in the left side of the colon mucosa, mimicked activity of IBD. However, a diagnosis of CMV colitis was based on the presence of CMV IgM antibodies, a seroconversion of CMV IgG antibodies, presence of CMV DNA in plasma and the finding af CMV DNA in biopsies from the intestinal mucosa. The patient responded to treatment with ganciclovir. This case highlights that a positive (18)F-FDG PET/CT scan of the colon can be due to CMV colitis.

Ejemplares similares