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BRCA2 and Other DDR Genes in Prostate Cancer

Germline and somatic aberrations in DNA damage repair (DDR) genes are more prevalent in prostate cancer than previously recognized, with BRCA2 as the most commonly altered gene. Germline mutations in BRCA2 have been linked to poor prognosis when patients are managed under the protocols currently app...

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Detalles Bibliográficos
Autores principales:	Nombela, Paz, Lozano, Rebeca, Aytes, Alvaro, Mateo, Joaquin, Olmos, David, Castro, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468860/ https://www.ncbi.nlm.nih.gov/pubmed/30871108 http://dx.doi.org/10.3390/cancers11030352

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