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Nicotine Induces Resistance to Erlotinib Therapy in Non-Small-Cell Lung Cancer Cells Treated with Serum from Human Patients

Previously, we reported that nicotine reduces erlotinib sensitivity in a xenograft model of PC9, an epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI)-sensitive non-small-cell lung cancer cell line. The present study examined whether smoking induces erlotinib resistance in vitro....

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Detalles Bibliográficos
Autores principales:	Imabayashi, Tatsuya, Uchino, Junji, Osoreda, Hisayuki, Tanimura, Keiko, Chihara, Yusuke, Tamiya, Nobuyo, Kaneko, Yoshiko, Yamada, Tadaaki, Takayama, Koichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468898/ https://www.ncbi.nlm.nih.gov/pubmed/30818860 http://dx.doi.org/10.3390/cancers11030282

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