Cargando…
Cancer Radiotherapy: Enhanced Radiosensitization by Gold Nanoparticles with Acid‐Triggered Aggregation in Cancer Radiotherapy (Adv. Sci. 8/2019)
In article number 1801806, Xing‐Jie Liang, Jianfeng Liu, and co‐workers develop a gold nanoparticles (GNPs) system with acid‐triggered aggregation as a radiosensitizer. With a sensitizer enhancement ratio (SER) value of 1.730 (vs. single GNPs of 1.16), this GNPs system improves sensitivity of MCF‐7...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468962/ http://dx.doi.org/10.1002/advs.201970050 |
_version_ | 1783411548523331584 |
---|---|
author | Zhang, Yumin Huang, Fan Ren, Chunhua Liu, Jinjian Yang, Lijun Chen, Shizhu Chang, Jinglin Yang, Cuihong Wang, Weiwei Zhang, Chuangnian Liu, Qiang Liang, Xing‐Jie Liu, Jianfeng |
author_facet | Zhang, Yumin Huang, Fan Ren, Chunhua Liu, Jinjian Yang, Lijun Chen, Shizhu Chang, Jinglin Yang, Cuihong Wang, Weiwei Zhang, Chuangnian Liu, Qiang Liang, Xing‐Jie Liu, Jianfeng |
author_sort | Zhang, Yumin |
collection | PubMed |
description | In article number 1801806, Xing‐Jie Liang, Jianfeng Liu, and co‐workers develop a gold nanoparticles (GNPs) system with acid‐triggered aggregation as a radiosensitizer. With a sensitizer enhancement ratio (SER) value of 1.730 (vs. single GNPs of 1.16), this GNPs system improves sensitivity of MCF‐7 cells and MCF‐7 tumor xenograft to ionizing radiation. This work provides a strategy for fabricating radiosensitizer by in situ acid‐triggered nano‐aggregates formation. [Image: see text] |
format | Online Article Text |
id | pubmed-6468962 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-64689622019-04-23 Cancer Radiotherapy: Enhanced Radiosensitization by Gold Nanoparticles with Acid‐Triggered Aggregation in Cancer Radiotherapy (Adv. Sci. 8/2019) Zhang, Yumin Huang, Fan Ren, Chunhua Liu, Jinjian Yang, Lijun Chen, Shizhu Chang, Jinglin Yang, Cuihong Wang, Weiwei Zhang, Chuangnian Liu, Qiang Liang, Xing‐Jie Liu, Jianfeng Adv Sci (Weinh) Inside Back Cover In article number 1801806, Xing‐Jie Liang, Jianfeng Liu, and co‐workers develop a gold nanoparticles (GNPs) system with acid‐triggered aggregation as a radiosensitizer. With a sensitizer enhancement ratio (SER) value of 1.730 (vs. single GNPs of 1.16), this GNPs system improves sensitivity of MCF‐7 cells and MCF‐7 tumor xenograft to ionizing radiation. This work provides a strategy for fabricating radiosensitizer by in situ acid‐triggered nano‐aggregates formation. [Image: see text] John Wiley and Sons Inc. 2019-04-17 /pmc/articles/PMC6468962/ http://dx.doi.org/10.1002/advs.201970050 Text en © 2019 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Inside Back Cover Zhang, Yumin Huang, Fan Ren, Chunhua Liu, Jinjian Yang, Lijun Chen, Shizhu Chang, Jinglin Yang, Cuihong Wang, Weiwei Zhang, Chuangnian Liu, Qiang Liang, Xing‐Jie Liu, Jianfeng Cancer Radiotherapy: Enhanced Radiosensitization by Gold Nanoparticles with Acid‐Triggered Aggregation in Cancer Radiotherapy (Adv. Sci. 8/2019) |
title | Cancer Radiotherapy: Enhanced Radiosensitization by Gold Nanoparticles with Acid‐Triggered Aggregation in Cancer Radiotherapy (Adv. Sci. 8/2019) |
title_full | Cancer Radiotherapy: Enhanced Radiosensitization by Gold Nanoparticles with Acid‐Triggered Aggregation in Cancer Radiotherapy (Adv. Sci. 8/2019) |
title_fullStr | Cancer Radiotherapy: Enhanced Radiosensitization by Gold Nanoparticles with Acid‐Triggered Aggregation in Cancer Radiotherapy (Adv. Sci. 8/2019) |
title_full_unstemmed | Cancer Radiotherapy: Enhanced Radiosensitization by Gold Nanoparticles with Acid‐Triggered Aggregation in Cancer Radiotherapy (Adv. Sci. 8/2019) |
title_short | Cancer Radiotherapy: Enhanced Radiosensitization by Gold Nanoparticles with Acid‐Triggered Aggregation in Cancer Radiotherapy (Adv. Sci. 8/2019) |
title_sort | cancer radiotherapy: enhanced radiosensitization by gold nanoparticles with acid‐triggered aggregation in cancer radiotherapy (adv. sci. 8/2019) |
topic | Inside Back Cover |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468962/ http://dx.doi.org/10.1002/advs.201970050 |
work_keys_str_mv | AT zhangyumin cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 AT huangfan cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 AT renchunhua cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 AT liujinjian cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 AT yanglijun cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 AT chenshizhu cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 AT changjinglin cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 AT yangcuihong cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 AT wangweiwei cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 AT zhangchuangnian cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 AT liuqiang cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 AT liangxingjie cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 AT liujianfeng cancerradiotherapyenhancedradiosensitizationbygoldnanoparticleswithacidtriggeredaggregationincancerradiotherapyadvsci82019 |