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Role of MAML1 in targeted therapy against the esophageal cancer stem cells

BACKGROUND: Esophageal cancer is the sixth-leading cause of cancer-related deaths worldwide. Cancer stem cells (CSCs) are the main reason for tumor relapse in esophageal squamous cell carcinoma (ESCC). The NOTCH pathway is important in preservation of CSCs, therefore it is possible to target such ce...

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Detalles Bibliográficos
Autores principales:	Moghbeli, Meysam, Mosannen Mozaffari, Hooman, Memar, Bahram, Forghanifard, Mohammad Mahdi, Gholamin, Mehran, Abbaszadegan, Mohammad Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469193/ https://www.ncbi.nlm.nih.gov/pubmed/30992079 http://dx.doi.org/10.1186/s12967-019-1876-5

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