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Interleukin-35 modulates the balance between viral specific CD4(+)CD25(+)CD127(dim/-) regulatory T cells and T helper 17 cells in chronic hepatitis B virus infection

BACKGROUND: Interleukin (IL)-35 regulates imbalance between regulatory T cells (Tregs) and T helper (Th) 17 cells, leading to an important modulator in autoimmune disorder, cancer, and infectious diseases. Our previous study revealed an immunosuppressive activity of IL-35 in chronic hepatitis B viru...

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Detalles Bibliográficos
Autores principales: Yang, Lanlan, Jia, Shengnan, Shao, Xue, Liu, Siqi, Zhang, Qian, Song, Jie, Wang, Wudong, Jin, Zhenjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469219/
https://www.ncbi.nlm.nih.gov/pubmed/30992023
http://dx.doi.org/10.1186/s12985-019-1158-0