Cargando…

Clinical presentation and outcome after anterior cervical discectomy and fusion for degenerative cervical disc disease

BACKGROUND: Anterior cervical discectomy and fusion (ACDF) is a well-described surgical approach for symptomatic degenerative cervical disc disease which does not respond to conservative management. In the present study, we assessed clinical presentation and outcomes of ACDF. MATERIALS AND METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales: Srikhande, Ninad N, Kumar, V A Kiran, Sai Kiran, N A, Ghosh, Amrita, Pal, Ranabir, Moscote-Salazar, Luis Rafael, Kumar, V Anil, Reddy, Vishnu Vardhan, Agrawal, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469327/
https://www.ncbi.nlm.nih.gov/pubmed/31000977
http://dx.doi.org/10.4103/jcvjs.JCVJS_87_18
_version_ 1783411624464351232
author Srikhande, Ninad N
Kumar, V A Kiran
Sai Kiran, N A
Ghosh, Amrita
Pal, Ranabir
Moscote-Salazar, Luis Rafael
Kumar, V Anil
Reddy, Vishnu Vardhan
Agrawal, Amit
author_facet Srikhande, Ninad N
Kumar, V A Kiran
Sai Kiran, N A
Ghosh, Amrita
Pal, Ranabir
Moscote-Salazar, Luis Rafael
Kumar, V Anil
Reddy, Vishnu Vardhan
Agrawal, Amit
author_sort Srikhande, Ninad N
collection PubMed
description BACKGROUND: Anterior cervical discectomy and fusion (ACDF) is a well-described surgical approach for symptomatic degenerative cervical disc disease which does not respond to conservative management. In the present study, we assessed clinical presentation and outcomes of ACDF. MATERIALS AND METHODS: The present study was conducted from October 1, 2015, to October 31, 2017, in the Department of Neurosurgery, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, among 100 consecutive adult patients who underwent single- or two-level ACDF for degenerative cervical disc disease. RESULTS: The mean age was 47.2 ± 12.8 years (range: 20–74 years). Majority of the patients were male (86/100). Presenting symptoms were neck pain (77%), limb weakness (73%), paresthesias (53%), radicular pain (49%), stiffness in limbs (16%), and bladder involvement (13%). Fusion was done with stand-alone titanium cage/bone graft or titanium cage/bone graft with anterior cervical plate. At the time of discharge, significant improvement in preoperative symptoms (neck pain [47/77-61%], radicular pain [31/49-63%], limb weakness [53/73-72.6%], paresthesias [44/53-83%], stiffness in limbs [13/16-81%], and bladder symptoms [8/13-61%]) was reported by majority of these patients. Majority of these patients also reported improvement in preoperative sensory deficits at the time of discharge. Postoperative complications were hoarseness of voice (22%), dysphagia (16%), deterioration of motor power (8%), and postoperative hematoma (7%). CONCLUSIONS: A significant proportion of patients with degenerative cervical disc disease show remarkable recovery after ACDF.
format Online
Article
Text
id pubmed-6469327
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-64693272019-04-18 Clinical presentation and outcome after anterior cervical discectomy and fusion for degenerative cervical disc disease Srikhande, Ninad N Kumar, V A Kiran Sai Kiran, N A Ghosh, Amrita Pal, Ranabir Moscote-Salazar, Luis Rafael Kumar, V Anil Reddy, Vishnu Vardhan Agrawal, Amit J Craniovertebr Junction Spine Original Article BACKGROUND: Anterior cervical discectomy and fusion (ACDF) is a well-described surgical approach for symptomatic degenerative cervical disc disease which does not respond to conservative management. In the present study, we assessed clinical presentation and outcomes of ACDF. MATERIALS AND METHODS: The present study was conducted from October 1, 2015, to October 31, 2017, in the Department of Neurosurgery, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, among 100 consecutive adult patients who underwent single- or two-level ACDF for degenerative cervical disc disease. RESULTS: The mean age was 47.2 ± 12.8 years (range: 20–74 years). Majority of the patients were male (86/100). Presenting symptoms were neck pain (77%), limb weakness (73%), paresthesias (53%), radicular pain (49%), stiffness in limbs (16%), and bladder involvement (13%). Fusion was done with stand-alone titanium cage/bone graft or titanium cage/bone graft with anterior cervical plate. At the time of discharge, significant improvement in preoperative symptoms (neck pain [47/77-61%], radicular pain [31/49-63%], limb weakness [53/73-72.6%], paresthesias [44/53-83%], stiffness in limbs [13/16-81%], and bladder symptoms [8/13-61%]) was reported by majority of these patients. Majority of these patients also reported improvement in preoperative sensory deficits at the time of discharge. Postoperative complications were hoarseness of voice (22%), dysphagia (16%), deterioration of motor power (8%), and postoperative hematoma (7%). CONCLUSIONS: A significant proportion of patients with degenerative cervical disc disease show remarkable recovery after ACDF. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6469327/ /pubmed/31000977 http://dx.doi.org/10.4103/jcvjs.JCVJS_87_18 Text en Copyright: © 2019 Journal of Craniovertebral Junction and Spine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Srikhande, Ninad N
Kumar, V A Kiran
Sai Kiran, N A
Ghosh, Amrita
Pal, Ranabir
Moscote-Salazar, Luis Rafael
Kumar, V Anil
Reddy, Vishnu Vardhan
Agrawal, Amit
Clinical presentation and outcome after anterior cervical discectomy and fusion for degenerative cervical disc disease
title Clinical presentation and outcome after anterior cervical discectomy and fusion for degenerative cervical disc disease
title_full Clinical presentation and outcome after anterior cervical discectomy and fusion for degenerative cervical disc disease
title_fullStr Clinical presentation and outcome after anterior cervical discectomy and fusion for degenerative cervical disc disease
title_full_unstemmed Clinical presentation and outcome after anterior cervical discectomy and fusion for degenerative cervical disc disease
title_short Clinical presentation and outcome after anterior cervical discectomy and fusion for degenerative cervical disc disease
title_sort clinical presentation and outcome after anterior cervical discectomy and fusion for degenerative cervical disc disease
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469327/
https://www.ncbi.nlm.nih.gov/pubmed/31000977
http://dx.doi.org/10.4103/jcvjs.JCVJS_87_18
work_keys_str_mv AT srikhandeninadn clinicalpresentationandoutcomeafteranteriorcervicaldiscectomyandfusionfordegenerativecervicaldiscdisease
AT kumarvakiran clinicalpresentationandoutcomeafteranteriorcervicaldiscectomyandfusionfordegenerativecervicaldiscdisease
AT saikiranna clinicalpresentationandoutcomeafteranteriorcervicaldiscectomyandfusionfordegenerativecervicaldiscdisease
AT ghoshamrita clinicalpresentationandoutcomeafteranteriorcervicaldiscectomyandfusionfordegenerativecervicaldiscdisease
AT palranabir clinicalpresentationandoutcomeafteranteriorcervicaldiscectomyandfusionfordegenerativecervicaldiscdisease
AT moscotesalazarluisrafael clinicalpresentationandoutcomeafteranteriorcervicaldiscectomyandfusionfordegenerativecervicaldiscdisease
AT kumarvanil clinicalpresentationandoutcomeafteranteriorcervicaldiscectomyandfusionfordegenerativecervicaldiscdisease
AT reddyvishnuvardhan clinicalpresentationandoutcomeafteranteriorcervicaldiscectomyandfusionfordegenerativecervicaldiscdisease
AT agrawalamit clinicalpresentationandoutcomeafteranteriorcervicaldiscectomyandfusionfordegenerativecervicaldiscdisease