Novel CSF biomarkers in genetic frontotemporal dementia identified by proteomics

OBJECTIVE: To identify novel CSF biomarkers in GRN‐associated frontotemporal dementia (FTD) by proteomics using mass spectrometry (MS). METHODS: Unbiased MS was applied to CSF samples from 19 presymptomatic and 9 symptomatic GRN mutation carriers and 24 noncarriers. Protein abundances were compared...

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Detalles Bibliográficos
Autores principales: van der Ende, Emma L., Meeter, Lieke H., Stingl, Christoph, van Rooij, Jeroen G. J., Stoop, Marcel P., Nijholt, Diana A. T., Sanchez‐Valle, Raquel, Graff, Caroline, Öijerstedt, Linn, Grossman, Murray, McMillan, Corey, Pijnenburg, Yolande A. L., Laforce, Robert, Binetti, Giuliano, Benussi, Luisa, Ghidoni, Roberta, Luider, Theo M., Seelaar, Harro, van Swieten, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469343/
https://www.ncbi.nlm.nih.gov/pubmed/31019994
http://dx.doi.org/10.1002/acn3.745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469343/
https://www.ncbi.nlm.nih.gov/pubmed/31019994
http://dx.doi.org/10.1002/acn3.745

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