Cargando…

MicroRNAs and Long Non-coding RNAs in Genetic Diseases

Since the discovery and classification of non-coding RNAs, their roles have gained great attention. In this respect, microRNAs and long non-coding RNAs have been firmly demonstrated to be linked to regulation of gene expression and onset of human diseases, including rare genetic diseases; therefore...

Descripción completa

Detalles Bibliográficos
Autores principales:	Finotti, Alessia, Fabbri, Enrica, Lampronti, Ilaria, Gasparello, Jessica, Borgatti, Monica, Gambari, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2019
Materias:	Current Opinion
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469593/ https://www.ncbi.nlm.nih.gov/pubmed/30610665 http://dx.doi.org/10.1007/s40291-018-0380-6

Ejemplares similares

Differential effects on the miRNome of the treatment of human airway epithelial Calu-3 cells with peptide-nucleic acids (PNAs) targeting microRNAs miR-101-3p and miR-145-5p: Next generation sequencing datasets
por: Gasparello, Jessica, et al.
Publicado: (2021)

Tackling the COVID-19 “cytokine storm” with microRNA mimics directly targeting the 3’UTR of pro-inflammatory mRNAs
por: Gasparello, Jessica, et al.
Publicado: (2021)

A Peptide Nucleic Acid against MicroRNA miR-145-5p Enhances the Expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Calu-3 Cells
por: Fabbri, Enrica, et al.
Publicado: (2017)

Combined Treatment of Cancer Cells Using Allyl Palladium Complexes Bearing Purine-Based NHC Ligands and Molecules Targeting MicroRNAs miR-221-3p and miR-222-3p: Synergistic Effects on Apoptosis
por: Tupini, Chiara, et al.
Publicado: (2023)

Demonstrating specificity of bioactive peptide nucleic acids (PNAs) targeting microRNAs for practical laboratory classes of applied biochemistry and pharmacology
por: Gasparello, Jessica, et al.
Publicado: (2019)

Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions
por: Finotti, Alessia, et al.
Publicado: (2015)

Increase of microRNA-210, Decrease of Raptor Gene Expression and Alteration of Mammalian Target of Rapamycin Regulated Proteins following Mithramycin Treatment of Human Erythroid Cells
por: Bianchi, Nicoletta, et al.
Publicado: (2015)

BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression
por: Gasparello, Jessica, et al.
Publicado: (2017)

A Peptide-Nucleic Acid Targeting miR-335-5p Enhances Expression of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene with the Possible Involvement of the CFTR Scaffolding Protein NHERF1
por: Tamanini, Anna, et al.
Publicado: (2021)

The Cystic Fibrosis Transmembrane Conductance Regulator Gene (CFTR) Is under Post-Transcriptional Control of microRNAs: Analysis of the Effects of agomiRNAs Mimicking miR-145-5p, miR-101-3p, and miR-335-5p
por: Papi, Chiara, et al.
Publicado: (2023)

Enhancing the Expression of CFTR Using Antisense Molecules against MicroRNA miR-145-5p
por: Finotti, Alessia, et al.
Publicado: (2019)

Targeting miR-155-5p and miR-221-3p by peptide nucleic acids induces caspase-3 activation and apoptosis in temozolomide-resistant T98G glioma cells
por: Milani, Roberta, et al.
Publicado: (2019)

Peptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells
por: MONTAGNER, GIULIA, et al.
Publicado: (2015)

The rs368698783 (G>A) Polymorphism Affecting LYAR Binding to the Aγ-Globin Gene Is Associated with High Fetal Hemoglobin (HbF) in β-Thalassemia Erythroid Precursor Cells Treated with HbF Inducers
por: Zuccato, Cristina, et al.
Publicado: (2023)

A Peptide Nucleic Acid (PNA) Masking the miR-145-5p Binding Site of the 3′UTR of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) mRNA Enhances CFTR Expression in Calu-3 Cells
por: Sultan, Shaiq, et al.
Publicado: (2020)

In vitro induction of interleukin-8 by SARS-CoV-2 Spike protein is inhibited in bronchial epithelial IB3-1 cells by a miR-93-5p agomiR
por: Gasparello, Jessica, et al.
Publicado: (2021)

Role of Cystic Fibrosis Bronchial Epithelium in Neutrophil Chemotaxis
por: Cabrini, Giulio, et al.
Publicado: (2020)

MicroRNAs miR-584-5p and miR-425-3p Are Up-Regulated in Plasma of Colorectal Cancer (CRC) Patients: Targeting with Inhibitor Peptide Nucleic Acids Is Associated with Induction of Apoptosis in Colon Cancer Cell Lines
por: Gasparello, Jessica, et al.
Publicado: (2022)

A Rational Approach to Drug Repositioning in β-thalassemia: Induction of Fetal Hemoglobin by Established Drugs
por: Prosdocimi, Marco, et al.
Publicado: (2022)

Sulforaphane inhibits the expression of interleukin-6 and interleukin-8 induced in bronchial epithelial IB3-1 cells by exposure to the SARS-CoV-2 Spike protein
por: Gasparello, Jessica, et al.
Publicado: (2021)

Oncomirs: The potential role of non-coding microRNAs in understanding cancer
por: Manikandan, Jayapal, et al.
Publicado: (2008)

UPF1 silenced cellular model systems for screening of read-through agents active on β(0)39 thalassemia point mutation
por: Salvatori, Francesca, et al.
Publicado: (2018)

Treatment of Erythroid Precursor Cells from β-Thalassemia Patients with Cinchona Alkaloids: Induction of Fetal Hemoglobin Production
por: Zuccato, Cristina, et al.
Publicado: (2021)

Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae
por: Altamura, Emiliano, et al.
Publicado: (2016)

Effects of Mithramycin on BCL11A Gene Expression and on the Interaction of the BCL11A Transcriptional Complex to γ-Globin Gene Promoter Sequences
por: Finotti, Alessia, et al.
Publicado: (2023)

Liquid biopsy in mice bearing colorectal carcinoma xenografts: gateways regulating the levels of circulating tumor DNA (ctDNA) and miRNA (ctmiRNA)
por: Gasparello, Jessica, et al.
Publicado: (2018)

Pro-apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro
por: Lampronti, Ilaria, et al.
Publicado: (2020)

Efficient Delivery of MicroRNA and AntimiRNA Molecules Using an Argininocalix[4]arene Macrocycle
por: Gasparello, Jessica, et al.
Publicado: (2019)

Corilagin Induces High Levels of Apoptosis in the Temozolomide-Resistant T98G Glioma Cell Line
por: Milani, Roberta, et al.
Publicado: (2018)

microRNAs: a role in drug resistance in parasitic nematodes?
por: Devaney, Eileen, et al.
Publicado: (2010)

PCR detection of segmented filamentous bacteria in the terminal ileum of patients with ulcerative colitis
por: Finotti, Alessia, et al.
Publicado: (2017)

Regulation of IL-8 gene expression in gliomas by microRNA miR-93
por: Fabbri, Enrica, et al.
Publicado: (2015)

Tuning the Loading and Release Properties of MicroRNA-Silencing Porous Silicon Nanoparticles by Using Chemically Diverse Peptide Nucleic Acid Payloads
por: Neri, Martina, et al.
Publicado: (2021)

Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of β-Thalassemia and Sickle-Cell Anemia
por: Bianchi, Nicoletta, et al.
Publicado: (2009)

Modulation of the Expression of the Proinflammatory IL-8 Gene in Cystic Fibrosis Cells by Extracts Deriving from Olive Mill Waste Water
por: Lampronti, Ilaria, et al.
Publicado: (2013)

Primate-specific Long Non-coding RNAs and MicroRNAs
por: Awan, Hassaan Mehboob, et al.
Publicado: (2017)

Role of MicroRNAs and Long Non-Coding RNAs in Sarcopenia
por: Lee, Jihui, et al.
Publicado: (2022)

MicroRNAs and Long Non-Coding RNAs in Adrenocortical Carcinoma
por: Detomas, Mario, et al.
Publicado: (2022)

MicroRNA Mimics or Inhibitors as Antiviral Therapeutic Approaches Against COVID-19
por: Hum, Christine, et al.
Publicado: (2021)

High-Throughput Methods to Detect Long Non-Coding RNAs
por: Uchida, Shizuka
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_1sam1s4e9qec1utvhb2c87189c