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CRISPR/Cas precision: do we need to worry about off-targeting in plants?

The CRISPR/Cas technology has recently become the tool of choice for targeted genome modification in plants and beyond. Although CRSIPR/Cas offers a rapid and facile way of introducing changes at genomic loci of interest, its application is associated with off-targeting, i.e. introduction of uninten...

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Detalles Bibliográficos
Autores principales: Hahn, Florian, Nekrasov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469637/
https://www.ncbi.nlm.nih.gov/pubmed/30426198
http://dx.doi.org/10.1007/s00299-018-2355-9

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