Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO)

Sepsis and septic shock are major causes of mortality during chemotherapy-induced neutropenia for malignancies requiring urgent treatment. Thus, awareness of the presenting characteristics and prompt management is most important. Improved management of sepsis during neutropenia may reduce the mortal...

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Autores principales: Kochanek, Matthias, Schalk, E., von Bergwelt-Baildon, M., Beutel, G., Buchheidt, D., Hentrich, M., Henze, L., Kiehl, M., Liebregts, T., von Lilienfeld-Toal, M., Classen, A., Mellinghoff, S., Penack, O., Piepel, C., Böll, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469653/
https://www.ncbi.nlm.nih.gov/pubmed/30796468
http://dx.doi.org/10.1007/s00277-019-03622-0
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author Kochanek, Matthias
Schalk, E.
von Bergwelt-Baildon, M.
Beutel, G.
Buchheidt, D.
Hentrich, M.
Henze, L.
Kiehl, M.
Liebregts, T.
von Lilienfeld-Toal, M.
Classen, A.
Mellinghoff, S.
Penack, O.
Piepel, C.
Böll, B.
author_facet Kochanek, Matthias
Schalk, E.
von Bergwelt-Baildon, M.
Beutel, G.
Buchheidt, D.
Hentrich, M.
Henze, L.
Kiehl, M.
Liebregts, T.
von Lilienfeld-Toal, M.
Classen, A.
Mellinghoff, S.
Penack, O.
Piepel, C.
Böll, B.
author_sort Kochanek, Matthias
collection PubMed
description Sepsis and septic shock are major causes of mortality during chemotherapy-induced neutropenia for malignancies requiring urgent treatment. Thus, awareness of the presenting characteristics and prompt management is most important. Improved management of sepsis during neutropenia may reduce the mortality of cancer therapies. However, optimal management may differ between neutropenic and non-neutropenic patients. The aim of the current guideline is to give evidence-based recommendations for hematologists, oncologists, and intensive care physicians on how to manage adult patients with neutropenia and sepsis.
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spelling pubmed-64696532019-05-03 Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO) Kochanek, Matthias Schalk, E. von Bergwelt-Baildon, M. Beutel, G. Buchheidt, D. Hentrich, M. Henze, L. Kiehl, M. Liebregts, T. von Lilienfeld-Toal, M. Classen, A. Mellinghoff, S. Penack, O. Piepel, C. Böll, B. Ann Hematol Review Article Sepsis and septic shock are major causes of mortality during chemotherapy-induced neutropenia for malignancies requiring urgent treatment. Thus, awareness of the presenting characteristics and prompt management is most important. Improved management of sepsis during neutropenia may reduce the mortality of cancer therapies. However, optimal management may differ between neutropenic and non-neutropenic patients. The aim of the current guideline is to give evidence-based recommendations for hematologists, oncologists, and intensive care physicians on how to manage adult patients with neutropenia and sepsis. Springer Berlin Heidelberg 2019-02-22 2019 /pmc/articles/PMC6469653/ /pubmed/30796468 http://dx.doi.org/10.1007/s00277-019-03622-0 Text en © The Author(s) 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Review Article
Kochanek, Matthias
Schalk, E.
von Bergwelt-Baildon, M.
Beutel, G.
Buchheidt, D.
Hentrich, M.
Henze, L.
Kiehl, M.
Liebregts, T.
von Lilienfeld-Toal, M.
Classen, A.
Mellinghoff, S.
Penack, O.
Piepel, C.
Böll, B.
Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO)
title Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO)
title_full Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO)
title_fullStr Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO)
title_full_unstemmed Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO)
title_short Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO)
title_sort management of sepsis in neutropenic cancer patients: 2018 guidelines from the infectious diseases working party (agiho) and intensive care working party (ichop) of the german society of hematology and medical oncology (dgho)
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469653/
https://www.ncbi.nlm.nih.gov/pubmed/30796468
http://dx.doi.org/10.1007/s00277-019-03622-0
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