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A stochastic SIR network epidemic model with preventive dropping of edges

A Markovian Susceptible [Formula: see text] Infectious [Formula: see text] Recovered (SIR) model is considered for the spread of an epidemic on a configuration model network, in which susceptible individuals may take preventive measures by dropping edges to infectious neighbours. An effective degree...

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Autores principales: Ball, Frank, Britton, Tom, Leung, Ka Yin, Sirl, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469721/
https://www.ncbi.nlm.nih.gov/pubmed/30868213
http://dx.doi.org/10.1007/s00285-019-01329-4
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author Ball, Frank
Britton, Tom
Leung, Ka Yin
Sirl, David
author_facet Ball, Frank
Britton, Tom
Leung, Ka Yin
Sirl, David
author_sort Ball, Frank
collection PubMed
description A Markovian Susceptible [Formula: see text] Infectious [Formula: see text] Recovered (SIR) model is considered for the spread of an epidemic on a configuration model network, in which susceptible individuals may take preventive measures by dropping edges to infectious neighbours. An effective degree formulation of the model is used in conjunction with the theory of density dependent population processes to obtain a law of large numbers and a functional central limit theorem for the epidemic as the population size [Formula: see text] , assuming that the degrees of individuals are bounded. A central limit theorem is conjectured for the final size of the epidemic. The results are obtained for both the Molloy–Reed (in which the degrees of individuals are deterministic) and Newman–Strogatz–Watts (in which the degrees of individuals are independent and identically distributed) versions of the configuration model. The two versions yield the same limiting deterministic model but the asymptotic variances in the central limit theorems are greater in the Newman–Strogatz–Watts version. The basic reproduction number [Formula: see text] and the process of susceptible individuals in the limiting deterministic model, for the model with dropping of edges, are the same as for a corresponding SIR model without dropping of edges but an increased recovery rate, though, when [Formula: see text] , the probability of a major outbreak is greater in the model with dropping of edges. The results are specialised to the model without dropping of edges to yield conjectured central limit theorems for the final size of Markovian SIR epidemics on configuration-model networks, and for the size of the giant components of those networks. The theory is illustrated by numerical studies, which demonstrate that the asymptotic approximations are good, even for moderate N.
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spelling pubmed-64697212019-05-03 A stochastic SIR network epidemic model with preventive dropping of edges Ball, Frank Britton, Tom Leung, Ka Yin Sirl, David J Math Biol Article A Markovian Susceptible [Formula: see text] Infectious [Formula: see text] Recovered (SIR) model is considered for the spread of an epidemic on a configuration model network, in which susceptible individuals may take preventive measures by dropping edges to infectious neighbours. An effective degree formulation of the model is used in conjunction with the theory of density dependent population processes to obtain a law of large numbers and a functional central limit theorem for the epidemic as the population size [Formula: see text] , assuming that the degrees of individuals are bounded. A central limit theorem is conjectured for the final size of the epidemic. The results are obtained for both the Molloy–Reed (in which the degrees of individuals are deterministic) and Newman–Strogatz–Watts (in which the degrees of individuals are independent and identically distributed) versions of the configuration model. The two versions yield the same limiting deterministic model but the asymptotic variances in the central limit theorems are greater in the Newman–Strogatz–Watts version. The basic reproduction number [Formula: see text] and the process of susceptible individuals in the limiting deterministic model, for the model with dropping of edges, are the same as for a corresponding SIR model without dropping of edges but an increased recovery rate, though, when [Formula: see text] , the probability of a major outbreak is greater in the model with dropping of edges. The results are specialised to the model without dropping of edges to yield conjectured central limit theorems for the final size of Markovian SIR epidemics on configuration-model networks, and for the size of the giant components of those networks. The theory is illustrated by numerical studies, which demonstrate that the asymptotic approximations are good, even for moderate N. Springer Berlin Heidelberg 2019-03-13 2019 /pmc/articles/PMC6469721/ /pubmed/30868213 http://dx.doi.org/10.1007/s00285-019-01329-4 Text en © The Author(s) 2019 OpenAccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Article
Ball, Frank
Britton, Tom
Leung, Ka Yin
Sirl, David
A stochastic SIR network epidemic model with preventive dropping of edges
title A stochastic SIR network epidemic model with preventive dropping of edges
title_full A stochastic SIR network epidemic model with preventive dropping of edges
title_fullStr A stochastic SIR network epidemic model with preventive dropping of edges
title_full_unstemmed A stochastic SIR network epidemic model with preventive dropping of edges
title_short A stochastic SIR network epidemic model with preventive dropping of edges
title_sort stochastic sir network epidemic model with preventive dropping of edges
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469721/
https://www.ncbi.nlm.nih.gov/pubmed/30868213
http://dx.doi.org/10.1007/s00285-019-01329-4
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