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Selective colony area method for heterogeneous patient-derived tumor cell lines in anti-cancer drug screening system

We aimed to establish a fluorescence intensity-based colony area sweeping method by selecting the area of highest viability among patient-derived cancer cells (PDC) which has high tumor heterogeneity. Five gastric cancer cell lines and PDCs were screened with 24 small molecule compounds using a 3D m...

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Detalles Bibliográficos
Autores principales: Cho, Jang Ho, Kim, Ju-Sun, Kim, Seung Tae, Hong, Jung Yong, Park, Joon Oh, Park, Young Suk, Nam, Do-Hyun, Lee, Dong Woo, Lee, Jeeyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469764/
https://www.ncbi.nlm.nih.gov/pubmed/30995234
http://dx.doi.org/10.1371/journal.pone.0215080