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Selective colony area method for heterogeneous patient-derived tumor cell lines in anti-cancer drug screening system
We aimed to establish a fluorescence intensity-based colony area sweeping method by selecting the area of highest viability among patient-derived cancer cells (PDC) which has high tumor heterogeneity. Five gastric cancer cell lines and PDCs were screened with 24 small molecule compounds using a 3D m...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469764/ https://www.ncbi.nlm.nih.gov/pubmed/30995234 http://dx.doi.org/10.1371/journal.pone.0215080 |