Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting

The vaccine elicitation of broadly neutralizing responses is a central goal of HIV research. Recently, we elicited cross-clade neutralizing responses against the N terminus of the fusion peptide (FP), a critical component of the HIV-entry machinery. While the consistency of the elicited cross-clade...

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Detalles Bibliográficos
Autores principales: Cheng, Cheng, Xu, Kai, Kong, Rui, Chuang, Gwo-Yu, Corrigan, Angela R., Geng, Hui, Hill, Kurt R., Jafari, Alexander J., O’Dell, Sijy, Ou, Li, Rawi, Reda, Rowshan, Ariana P., Sarfo, Edward K., Sastry, Mallika, Saunders, Kevin O., Schmidt, Stephen D., Wang, Shuishu, Wu, Winston, Zhang, Baoshan, Doria-Rose, Nicole A., Haynes, Barton F., Scorpio, Diana G., Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469787/
https://www.ncbi.nlm.nih.gov/pubmed/30995238
http://dx.doi.org/10.1371/journal.pone.0215163

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