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Laxative effect of repeated Daiokanzoto is attributable to decrease in aquaporin-3 expression in the colon
Daiokanzoto (DKT) exerts its laxative effect via colonic inflammation caused by sennoside A in Daio (rhubarb). Previously, we showed that the laxative effect of sennoside A is related to decreased aquaporin-3 (AQP3) expression in mucosal epithelial cells due to colonic inflammation. We also found th...
Autores principales: | Kon, Risako, Yamamura, Miho, Matsunaga, Yukari, Kimura, Hiroshi, Minami, Moe, Kato, Saki, Ikarashi, Nobutomo, Sugiyama, Kiyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469848/ https://www.ncbi.nlm.nih.gov/pubmed/29380109 http://dx.doi.org/10.1007/s11418-018-1174-1 |
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