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Homeobox B13 G84E Mutation and Prostate Cancer Risk

BACKGROUND: The homeobox B13 (HOXB13) G84E mutation has been recommended for use in genetic counselling for prostate cancer (PCa), but the magnitude of PCa risk conferred by this mutation is uncertain. OBJECTIVE: To obtain precise risk estimates for mutation carriers and information on how these var...

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Detalles Bibliográficos
Autores principales: Nyberg, Tommy, Govindasami, Koveela, Leslie, Goska, Dadaev, Tokhir, Bancroft, Elizabeth, Ni Raghallaigh, Holly, Brook, Mark N., Hussain, Nafisa, Keating, Diana, Lee, Andrew, McMahon, Romayne, Morgan, Angela, Mullen, Andrea, Osborne, Andrea, Rageevakumar, Reshma, Kote-Jarai, Zsofia, Eeles, Rosalind, Antoniou, Antonis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470122/
https://www.ncbi.nlm.nih.gov/pubmed/30527799
http://dx.doi.org/10.1016/j.eururo.2018.11.015