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NDV-3A vaccination prevents C. albicans colonization of jugular vein catheters in mice

NDV-3A, a novel fungal vaccine undergoing clinical trials, contains a recombinant version of the Candida albicans rAls3 N-terminus protein (rAls3p-N) in aluminum hydroxide. In a Phase 1b/2a clinical trial, NDV-3A protected women from recurrent vulvovaginal candidiasis. Here, we reveal that active im...

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Detalles Bibliográficos
Autores principales: Alqarihi, Abdullah, Singh, Shakti, Edwards, John E., Ibrahim, Ashraf S., Uppuluri, Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470131/
https://www.ncbi.nlm.nih.gov/pubmed/30996274
http://dx.doi.org/10.1038/s41598-019-42517-y