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Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability
Parkinson’s disease (PD), with its characteristic loss of nigrostriatal dopaminergic neurons and deposition of α-synuclein in neurons, is often considered a neuronal disorder. However, in recent years substantial evidence has emerged to implicate glial cell types, such as astrocytes and microglia. I...
Autores principales: | Reynolds, Regina H., Botía, Juan, Nalls, Mike A., Hardy, John, Gagliano Taliun, Sarah A., Ryten, Mina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470136/ https://www.ncbi.nlm.nih.gov/pubmed/31016231 http://dx.doi.org/10.1038/s41531-019-0076-6 |
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