Conformational plasticity in the KcsA potassium channel pore helix revealed by homo-FRET studies

Potassium channels selectivity filter (SF) conformation is modulated by several factors, including ion-protein and protein-protein interactions. Here, we investigate the SF dynamics of a single Trp mutant of the potassium channel KcsA (W67) using polarized time-resolved fluorescence measurements. Fo...

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Detalles Bibliográficos
Autores principales: Renart, M. Lourdes, Giudici, A. Marcela, Poveda, José A., Fedorov, Aleksander, Berberan-Santos, Mário N., Prieto, Manuel, Díaz-García, Clara, González-Ros, José M., Coutinho, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470172/
https://www.ncbi.nlm.nih.gov/pubmed/30996281
http://dx.doi.org/10.1038/s41598-019-42405-5

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