Skin Directed Therapy in Cutaneous T-Cell Lymphoma

Skin directed therapies (SDTs) serve important roles in the treatment of early stage cutaneous T-cell lymphoma (CTCL)/mycosis fungoides (MF), as well as managing symptoms and improving quality of life of all stages. There are now numerous options for topical therapies that demonstrate high response...

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Detalles Bibliográficos
Autores principales: Tarabadkar, Erica S., Shinohara, Michi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470180/
https://www.ncbi.nlm.nih.gov/pubmed/31032224
http://dx.doi.org/10.3389/fonc.2019.00260
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author Tarabadkar, Erica S.
Shinohara, Michi M.
author_facet Tarabadkar, Erica S.
Shinohara, Michi M.
author_sort Tarabadkar, Erica S.
collection PubMed
description Skin directed therapies (SDTs) serve important roles in the treatment of early stage cutaneous T-cell lymphoma (CTCL)/mycosis fungoides (MF), as well as managing symptoms and improving quality of life of all stages. There are now numerous options for topical therapies that demonstrate high response rates, particularly in early/limited MF. Phototherapy retains an important role in treating MF, with increasing data supporting efficacy and long-term safety of both UVB and PUVA as well as some newer/targeted methodologies. Radiation therapy, including localized radiation and total skin electron beam therapy, continues to be a cornerstone of therapy for all stages of MF.
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spelling pubmed-64701802019-04-26 Skin Directed Therapy in Cutaneous T-Cell Lymphoma Tarabadkar, Erica S. Shinohara, Michi M. Front Oncol Oncology Skin directed therapies (SDTs) serve important roles in the treatment of early stage cutaneous T-cell lymphoma (CTCL)/mycosis fungoides (MF), as well as managing symptoms and improving quality of life of all stages. There are now numerous options for topical therapies that demonstrate high response rates, particularly in early/limited MF. Phototherapy retains an important role in treating MF, with increasing data supporting efficacy and long-term safety of both UVB and PUVA as well as some newer/targeted methodologies. Radiation therapy, including localized radiation and total skin electron beam therapy, continues to be a cornerstone of therapy for all stages of MF. Frontiers Media S.A. 2019-04-11 /pmc/articles/PMC6470180/ /pubmed/31032224 http://dx.doi.org/10.3389/fonc.2019.00260 Text en Copyright © 2019 Tarabadkar and Shinohara. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Tarabadkar, Erica S.
Shinohara, Michi M.
Skin Directed Therapy in Cutaneous T-Cell Lymphoma
title Skin Directed Therapy in Cutaneous T-Cell Lymphoma
title_full Skin Directed Therapy in Cutaneous T-Cell Lymphoma
title_fullStr Skin Directed Therapy in Cutaneous T-Cell Lymphoma
title_full_unstemmed Skin Directed Therapy in Cutaneous T-Cell Lymphoma
title_short Skin Directed Therapy in Cutaneous T-Cell Lymphoma
title_sort skin directed therapy in cutaneous t-cell lymphoma
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470180/
https://www.ncbi.nlm.nih.gov/pubmed/31032224
http://dx.doi.org/10.3389/fonc.2019.00260
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