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Role of TREK-1 in Health and Disease, Focus on the Central Nervous System

TREK-1 is the most studied background K(2P) channel. Its main role is to control cell excitability and maintain the membrane potential below the threshold of depolarization. TREK-1 is multi-regulated by a variety of physical and chemical stimuli which makes it a very promising and challenging target...

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Detalles Bibliográficos
Autores principales: Djillani, Alaeddine, Mazella, Jean, Heurteaux, Catherine, Borsotto, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470294/
https://www.ncbi.nlm.nih.gov/pubmed/31031627
http://dx.doi.org/10.3389/fphar.2019.00379