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Extensive mechanical tension promotes annulus fibrosus cell senescence through suppressing cellular autophagy
Background: Mechanical load contributes a lot to the initiation and progression of disc degeneration. Annulus fibrosus (AF) cell biology under mechanical tension remains largely unclear. Objective: The present study was aimed to investigate AF cell senescence under mechanical tension and the potenti...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Portland Press Ltd.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470409/ https://www.ncbi.nlm.nih.gov/pubmed/30910846 http://dx.doi.org/10.1042/BSR20190163 |