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Ageing in Pgc-1β(−/−) mice modelling mitochondrial dysfunction induces differential expression of a range of genes regulating ventricular electrophysiology
Mice deficient in mitochondrial promoter peroxisome proliferator activated receptor-γ co-activator-1β (Pgc-1β(−/−)) is a valuable model for metabolic diseases and has been found to present with several pathologies including ventricular arrhythmia. In the present study, our aim was to shed light on t...
Autores principales: | Edling, Charlotte E., Fazmin, Ibrahim T., Chadda, Karan R., Ahmad, Shiraz, Valli, Haseeb, Grace, Andrew A., Huang, Christopher L.-H., Jeevaratnam, Kamalan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470410/ https://www.ncbi.nlm.nih.gov/pubmed/30914453 http://dx.doi.org/10.1042/BSR20190127 |
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