Cargando…

Downregulation of the Netrin-1 Receptor UNC5b Underlies Increased Placental Angiogenesis in Human Gestational Diabetes Mellitus

Gestational diabetes mellitus (GDM) is a common metabolic disorder, defined by high blood glucose levels during pregnancy, which affects foetal and post-natal development. However, the cellular and molecular mechanisms of this detrimental condition are still poorly understood. A dysregulation in cir...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prieto, Catalina P., Casas, Bárbara S., Falcón, Paulina, Villanueva, Andrea, Lois, Pablo, Lattus, José, Palma, Verónica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470495/ https://www.ncbi.nlm.nih.gov/pubmed/30897795 http://dx.doi.org/10.3390/ijms20061408

Ejemplares similares

Netrin-1 acts as a non-canonical angiogenic factor produced by human Wharton’s jelly mesenchymal stem cells (WJ-MSC)
por: Prieto, Catalina P., et al.
Publicado: (2017)

Netrins and Their Roles in Placental Angiogenesis
por: Dakouane-Giudicelli, Mbarka, et al.
Publicado: (2014)

Hyperbaric Oxygen Increases Stem Cell Proliferation, Angiogenesis and Wound-Healing Ability of WJ-MSCs in Diabetic Mice
por: Peña-Villalobos, Isaac, et al.
Publicado: (2018)

Netrin (UNC-6) mediates dendritic self-avoidance
por: Smith, Cody J., et al.
Publicado: (2012)

UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity
por: Wang, Zheng, et al.
Publicado: (2014)

Selecting synaptic partners: GRASPing the role of UNC-6/netrin
por: Ch'ng, QueeLim
Publicado: (2011)

The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP
por: Norris, Adam D., et al.
Publicado: (2014)

A Systematic Analysis of the Role of Unc-5 Netrin Receptor A (UNC5A) in Human Cancers
por: Zhou, Zonglang, et al.
Publicado: (2022)

Experimental evidence for UNC-6 (netrin) axon guidance by stochastic fluctuations of intracellular UNC-40 (DCC) outgrowth activity
por: Kulkarni, Gauri, et al.
Publicado: (2013)

The Netrin-4/ Neogenin-1 axis promotes neuroblastoma cell survival and migration
por: Villanueva, Andrea A., et al.
Publicado: (2016)

UNC-6 (Netrin) Orients the Invasive Membrane of the Anchor Cell in C. elegans
por: Ziel, Joshua W., et al.
Publicado: (2008)

Molecular characterization of the netrin-1 UNC-5 receptor in Lucilia sericata larvae
por: Karamzadeh, Tahereh, et al.
Publicado: (2019)

Extracellular Matrix Regulates UNC-6 (Netrin) Axon Guidance by Controlling the Direction of Intracellular UNC-40 (DCC) Outgrowth Activity
por: Yang, Yong, et al.
Publicado: (2014)

TOM-1/tomosyn acts with the UNC-6/netrin receptor UNC-5 to inhibit growth cone protrusion in Caenorhabditis elegans
por: Mahadik, Snehal S., et al.
Publicado: (2023)

Netrin-1 binding to Unc5B regulates Blood-Retina Barrier integrity
por: Furtado, Jessica, et al.
Publicado: (2023)

Syntaxin-1 is necessary for UNC5A-C/Netrin-1-dependent macropinocytosis and chemorepulsion
por: Martínez-Mármol, Ramón, et al.
Publicado: (2023)

A short isoform of the UNC-6/Netrin receptor UNC-5 is required for growth cone polarity and robust growth cone protrusion in Caenorhabditis elegans
por: Mahadik, Snehal S., et al.
Publicado: (2023)

A short isoform of the UNC-6/Netrin receptor UNC-5 is required for growth cone polarity and robust growth cone protrusion in Caenorhabditis elegans
por: Mahadik, Snehal S., et al.
Publicado: (2023)

PKC α regulates netrin-1/UNC5B-mediated survival pathway in bladder cancer
por: Liu, Jiao, et al.
Publicado: (2014)

Netrin-1 promotes glioma growth by activating NF-κB via UNC5A
por: Chen, Jing-Ying, et al.
Publicado: (2017)

Growth cone repulsion to Netrin-1 depends on lipid raft microdomains enriched in UNC5 receptors
por: Hernaiz-Llorens, Marc, et al.
Publicado: (2020)

Netrin-1 promotes retinoblastoma-associated angiogenesis
por: Yang, Xiaosheng, et al.
Publicado: (2021)

The Netrin-1-Neogenin-1 signaling axis controls neuroblastoma cell migration via integrin-β1 and focal adhesion kinase activation
por: Villanueva, Andrea A., et al.
Publicado: (2021)

The Netrin-4/Laminin γ1/Neogenin-1 complex mediates migration in SK-N-SH neuroblastoma cells
por: Villanueva, Andrea A., et al.
Publicado: (2018)

Expression and Relationship of Netrin-1, DCC, UNC5B, and VEGF in Villous Tissues of Patients with Delayed Abortion
por: Dong, Fen, et al.
Publicado: (2022)

Netrin-1 inducing antiapoptotic effect of acute myeloid leukemia cells in a concentration-dependent manner through the Unc-5 netrin receptor B-focal adhesion kinase axis
por: Zhang, Kainan, et al.
Publicado: (2023)

Dorsal horn interneuron-derived Netrin-4 contributes to spinal sensitization in chronic pain via Unc5B
por: Hayano, Yasufumi, et al.
Publicado: (2016)

The netrin receptor UNC-40/DCC assembles a postsynaptic scaffold and sets the synaptic content of GABA(A) receptors
por: Zhou, Xin, et al.
Publicado: (2020)

Retracted: Expression and Relationship of Netrin-1, DCC, UNC5B, and VEGF in Villous Tissues of Patients with Delayed Abortion
por: Imaging, Contrast Media & Molecular
Publicado: (2023)

Netrin-1 in Glioblastoma Neovascularization: The New Partner in Crime?
por: Vásquez, Ximena, et al.
Publicado: (2021)

Flavin monooxygenases regulate Caenorhabditis elegans axon guidance and growth cone protrusion with UNC-6/Netrin signaling and Rac GTPases
por: Gujar, Mahekta R., et al.
Publicado: (2017)

Actin assembly and non-muscle myosin activity drive dendrite retraction in an UNC-6/Netrin dependent self-avoidance response
por: Sundararajan, Lakshmi, et al.
Publicado: (2019)

Netrin-1 receptor UNC5C cleavage by active δ-secretase enhances neurodegeneration, promoting Alzheimer’s disease pathologies
por: Chen, Guiqin, et al.
Publicado: (2021)

Reactive Oxygen Species are Essential for Placental Angiogenesis During Early Gestation
por: Yang, Yike, et al.
Publicado: (2022)

Gestational Diabetes Mellitus and Small-for-Gestational-Age: An Insight into the Placental Molecular Biomarkers
por: Giommi, Christian, et al.
Publicado: (2023)

Netrin-1 induces the anti-apoptotic and pro-survival effects of B-ALL cells through the Unc5b-MAPK axis
por: Huang, Lan, et al.
Publicado: (2022)

Netrin-1 mediates nerve innervation and angiogenesis leading to discogenic pain
por: Zheng, Bingjie, et al.
Publicado: (2022)

Placental Lipases in Pregnancies Complicated by Gestational Diabetes Mellitus (GDM)
por: Barrett, Helen L., et al.
Publicado: (2014)

Effects of Diet and Metformin on placental morphology in Gestational Diabetes Mellitus
por: Arshad, Rabia, et al.
Publicado: (2016)

Serum Levels and Placental Expression of NGAL in Gestational Diabetes Mellitus
por: Yin, Xiaoqian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hq11m63n17cfd08b8qgta7m081