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Is A Healthy Diet Associated with Lower Anthropometric and Glycemic Alterations in Predisposed Children Born from Mothers with Gestational Diabetes Mellitus?

Children born from mothers with gestational diabetes mellitus (GDM) are at high-risk of obesity and type 2 diabetes. To date, there is a lack of effective strategies to prevent these complications. The aim of this study was to evaluate the association between diet quality and anthropometric and glyc...

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Autores principales: Dugas, Camille, Bélanger, Mélissa, Perron, Julie, Weisnagel, S. John, Tchernof, André, Marc, Isabelle, Robitaille, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470518/
https://www.ncbi.nlm.nih.gov/pubmed/30866420
http://dx.doi.org/10.3390/nu11030570
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author Dugas, Camille
Bélanger, Mélissa
Perron, Julie
Weisnagel, S. John
Tchernof, André
Marc, Isabelle
Robitaille, Julie
author_facet Dugas, Camille
Bélanger, Mélissa
Perron, Julie
Weisnagel, S. John
Tchernof, André
Marc, Isabelle
Robitaille, Julie
author_sort Dugas, Camille
collection PubMed
description Children born from mothers with gestational diabetes mellitus (GDM) are at high-risk of obesity and type 2 diabetes. To date, there is a lack of effective strategies to prevent these complications. The aim of this study was to evaluate the association between diet quality and anthropometric and glycemic profiles of children exposed (GDM+) and unexposed (GDM–) to GDM. A total of 104 GDM+ and 38 GDM– children were included. Two 24-h dietary recall questionnaires were used to assess dietary intakes. The Healthy Eating Index adapted for the Canadian population (HEI-C) was used to assess diet quality. Spearman correlations adjusted for children’s age and sex were computed. Mean age was 6.0 ± 2.5 and 6.8 ± 2.3 years for GDM+ and GDM–, respectively (p = 0.03). Total HEI-C score was negatively associated with the android-to-gynoid fat mass ratio (r = −0.29, p = 0.03) and homeostasis model assessment for insulin resistance (HOMA-IR) index (r = −0.22, p = 0.04) in GDM+ children only. The prevalence of being overweight or obese during childhood was 4-fold higher among GDM+ children with a HEI-C score ≤70 compared to GDM+ children with a HEI-C score >70. Results of this study show that a healthy diet is associated with a better cardiometabolic health profile in GDM+ children, including a lower risk of being overweight or obese.
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spelling pubmed-64705182019-04-25 Is A Healthy Diet Associated with Lower Anthropometric and Glycemic Alterations in Predisposed Children Born from Mothers with Gestational Diabetes Mellitus? Dugas, Camille Bélanger, Mélissa Perron, Julie Weisnagel, S. John Tchernof, André Marc, Isabelle Robitaille, Julie Nutrients Article Children born from mothers with gestational diabetes mellitus (GDM) are at high-risk of obesity and type 2 diabetes. To date, there is a lack of effective strategies to prevent these complications. The aim of this study was to evaluate the association between diet quality and anthropometric and glycemic profiles of children exposed (GDM+) and unexposed (GDM–) to GDM. A total of 104 GDM+ and 38 GDM– children were included. Two 24-h dietary recall questionnaires were used to assess dietary intakes. The Healthy Eating Index adapted for the Canadian population (HEI-C) was used to assess diet quality. Spearman correlations adjusted for children’s age and sex were computed. Mean age was 6.0 ± 2.5 and 6.8 ± 2.3 years for GDM+ and GDM–, respectively (p = 0.03). Total HEI-C score was negatively associated with the android-to-gynoid fat mass ratio (r = −0.29, p = 0.03) and homeostasis model assessment for insulin resistance (HOMA-IR) index (r = −0.22, p = 0.04) in GDM+ children only. The prevalence of being overweight or obese during childhood was 4-fold higher among GDM+ children with a HEI-C score ≤70 compared to GDM+ children with a HEI-C score >70. Results of this study show that a healthy diet is associated with a better cardiometabolic health profile in GDM+ children, including a lower risk of being overweight or obese. MDPI 2019-03-07 /pmc/articles/PMC6470518/ /pubmed/30866420 http://dx.doi.org/10.3390/nu11030570 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Dugas, Camille
Bélanger, Mélissa
Perron, Julie
Weisnagel, S. John
Tchernof, André
Marc, Isabelle
Robitaille, Julie
Is A Healthy Diet Associated with Lower Anthropometric and Glycemic Alterations in Predisposed Children Born from Mothers with Gestational Diabetes Mellitus?
title Is A Healthy Diet Associated with Lower Anthropometric and Glycemic Alterations in Predisposed Children Born from Mothers with Gestational Diabetes Mellitus?
title_full Is A Healthy Diet Associated with Lower Anthropometric and Glycemic Alterations in Predisposed Children Born from Mothers with Gestational Diabetes Mellitus?
title_fullStr Is A Healthy Diet Associated with Lower Anthropometric and Glycemic Alterations in Predisposed Children Born from Mothers with Gestational Diabetes Mellitus?
title_full_unstemmed Is A Healthy Diet Associated with Lower Anthropometric and Glycemic Alterations in Predisposed Children Born from Mothers with Gestational Diabetes Mellitus?
title_short Is A Healthy Diet Associated with Lower Anthropometric and Glycemic Alterations in Predisposed Children Born from Mothers with Gestational Diabetes Mellitus?
title_sort is a healthy diet associated with lower anthropometric and glycemic alterations in predisposed children born from mothers with gestational diabetes mellitus?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470518/
https://www.ncbi.nlm.nih.gov/pubmed/30866420
http://dx.doi.org/10.3390/nu11030570
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