Ceramide Imbalance and Impaired TLR4-Mediated Autophagy in BMDM of an ORMDL3-Overexpressing Mouse Model

Increased orosomucoid-like 3 (ORMDL3) expression levels, due to single nucleotide polymorphisms (SNPs), have been associated with several inflammatory diseases, including asthma and inflammatory bowel diseases. ORMDL proteins inhibit serine palmitoyltransferase (SPT), the first rate-limiting enzyme...

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Detalles Bibliográficos
Autores principales: Kiefer, Kerstin, Casas, Josefina, García-López, Roberto, Vicente, Rubén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470650/
https://www.ncbi.nlm.nih.gov/pubmed/30897694
http://dx.doi.org/10.3390/ijms20061391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470650/
https://www.ncbi.nlm.nih.gov/pubmed/30897694
http://dx.doi.org/10.3390/ijms20061391

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