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Preparation, Characterization, and Stability Evaluation of Taste-Masking Lacosamide Microparticles

Lacosamide (LCM) is a third-generation antiepileptic drug. Selective action of the drug on voltage-gated sodium channels reduces side effects. Oral administration of LCM shows good pharmacokinetic profile. However, the bitter taste of LCM is a barrier to the development of oral formulations. In this...

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Detalles Bibliográficos
Autores principales: Han, Chang-Soo, Kim, Seungsu, Oh, Dong-Won, Yoon, Jeong Yeol, Park, Eun-Seok, Rhee, Yun-Seok, Kim, Ju-Young, Shin, Dae Hwan, Kim, Dong-Wook, Park, Chun-Woong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470747/
https://www.ncbi.nlm.nih.gov/pubmed/30917621
http://dx.doi.org/10.3390/ma12061000