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Enhanced Oral Bioavailability, Anti-Tumor Activity and Hepatoprotective Effect of 6-Shogaol Loaded in a Type of Novel Micelles of Polyethylene Glycol and Linoleic Acid Conjugate

6-shogaol is a promising anti-cancer and anti-inflammatory agent. However, the treatment effectiveness of 6-shogaol is limited by poor water solubility, poor oral absorption and rapid metabolism. Herein, 6-shogaol loaded in micelles (SMs) were designed to improve 6-shogaol’s solubility and bioavaila...

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Detalles Bibliográficos
Autores principales:	Zhang, Huiyun, Wang, Qilong, Sun, Congyong, Zhu, Yuan, Yang, Qiuxuan, Wei, Qiuyu, Chen, Jiaxin, Deng, Wenwen, Adu-Frimpong, Michael, Yu, Jiangnan, Xu, Ximing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470752/ https://www.ncbi.nlm.nih.gov/pubmed/30845761 http://dx.doi.org/10.3390/pharmaceutics11030107

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