Cargando…

Overview of the Manufacturing Methods of Solid Dispersion Technology for Improving the Solubility of Poorly Water-Soluble Drugs and Application to Anticancer Drugs

Approximately 40% of new chemical entities (NCEs), including anticancer drugs, have been reported as poorly water-soluble compounds. Anticancer drugs are classified into biologic drugs (monoclonal antibodies) and small molecule drugs (nonbiologic anticancer drugs) based on effectiveness and safety p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tran, Phuong, Pyo, Yong-Chul, Kim, Dong-Hyun, Lee, Sang-Eun, Kim, Jin-Ki, Park, Jeong-Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470797/ https://www.ncbi.nlm.nih.gov/pubmed/30893899 http://dx.doi.org/10.3390/pharmaceutics11030132

Ejemplares similares

Molecular Interactions in Solid Dispersions of Poorly Water-Soluble Drugs
por: Tran, Thao T. D., et al.
Publicado: (2020)

Fundamental aspects of solid dispersion technology for poorly soluble drugs
por: Huang, Yanbin, et al.
Publicado: (2014)

Insoluble Polymers in Solid Dispersions for Improving Bioavailability of Poorly Water-Soluble Drugs
por: Tran, Thao T.D., et al.
Publicado: (2020)

Improvement in solubility of poor water-soluble drugs by solid dispersion
por: Sareen, Swati, et al.
Publicado: (2012)

Solubility Enhancement of a Poorly Water Soluble Drug by Forming Solid Dispersions using Mechanochemical Activation
por: Rojas-Oviedo, I., et al.
Publicado: (2012)

A Review on Solid Dispersion and Carriers Used Therein for Solubility Enhancement of Poorly Water Soluble Drugs
por: Tekade, Avinash Ramrao, et al.
Publicado: (2020)

Solubility enhancement of some poorly soluble drugs by solid dispersion using Ziziphus spina-christi gum polymer
por: Alwossabi, Ameen M., et al.
Publicado: (2022)

Spray Congealing: An Emerging Technology to Prepare Solid Dispersions with Enhanced Oral Bioavailability of Poorly Water Soluble Drugs
por: Bertoni, Serena, et al.
Publicado: (2019)

Solubility Enhancement of a Poorly Water-Soluble Drug Using Hydrotropy and Mixed Hydrotropy-Based Solid Dispersion Techniques
por: Abdullah Ali, Hezha, et al.
Publicado: (2022)

Recent Technologies for Amorphization of Poorly Water-Soluble Drugs
por: Kim, Do-Hyun, et al.
Publicado: (2021)

Relative Contributions of Solubility and Mobility to the Stability of Amorphous Solid Dispersions of Poorly Soluble Drugs: A Molecular Dynamics Simulation Study
por: Brunsteiner, Michael, et al.
Publicado: (2018)

Improvement of In Vitro Dissolution of the Poor Water-Soluble Amlodipine Drug by Solid Dispersion with Irradiated Polyvinylpyrrolidone
por: Ghobashy, Mohamed Mohamady, et al.
Publicado: (2020)

Nanoconjugation and Encapsulation Strategies for Improving Drug Delivery and Therapeutic Efficacy of Poorly Water-Soluble Drugs
por: Tran, Thao T. D., et al.
Publicado: (2019)

Comparative study on solid self-nanoemulsifying drug delivery and solid dispersion system for enhanced solubility and bioavailability of ezetimibe
por: Rashid, Rehmana, et al.
Publicado: (2015)

Potential of solid dispersions to enhance solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs: newer formulation techniques, current marketed scenario and patents
por: Alshehri, Sultan, et al.
Publicado: (2020)

Enhanced dissolution of poorly soluble antiviral drugs from nanoparticles of cellulose acetate based solid dispersion matrices
por: Mazumder, Sonal, et al.
Publicado: (2017)

Pharmaceutical Dispersion Techniques for Dissolution and Bioavailability Enhancement of Poorly Water-Soluble Drugs
por: Zhang, Xingwang, et al.
Publicado: (2018)

Nanocrystalization: An Emerging Technology to Enhance the  Bioavailability of Poorly Soluble Drugs
por: Joshi, Kavita, et al.
Publicado: (2019)

Development of micro-fibrous solid dispersions of poorly water-soluble drugs in sucrose using temperature-controlled centrifugal spinning
por: Marano, Stefania, et al.
Publicado: (2016)

Crosslinked hydrogels—a promising class of insoluble solid molecular dispersion carriers for enhancing the delivery of poorly soluble drugs
por: Sun, Dajun D., et al.
Publicado: (2014)

The amorphous solid dispersion of the poorly soluble ABT-102 forms nano/microparticulate structures in aqueous medium: impact on solubility
por: Frank, Kerstin J, et al.
Publicado: (2012)

Analytical and Computational Methods for the Estimation of Drug-Polymer Solubility and Miscibility in Solid Dispersions Development
por: Medarević, Djordje, et al.
Publicado: (2019)

Self-Assembled Polymeric Micellar Nanoparticles as Nanocarriers for Poorly Soluble Anticancer Drug Ethaselen
por: Li, Xinru, et al.
Publicado: (2009)

Influence of Solid Drug Delivery System Formulation on Poorly Water-Soluble Drug Dissolution and Permeability
por: Krstić, Marko, et al.
Publicado: (2015)

Evaluation of the Solid Dispersion System Engineered from Mesoporous Silica and Polymers for the Poorly Water Soluble Drug Indomethacin: In Vitro and In Vivo
por: Xi, Ziyue, et al.
Publicado: (2020)

Cocrystal of Apixaban–Quercetin: Improving Solubility and Bioavailability of Drug Combination of Two Poorly Soluble Drugs
por: Zhang, Li, et al.
Publicado: (2021)

Hydrogel-Based Drug Delivery Systems for Poorly Water-Soluble Drugs
por: McKenzie, Matthew, et al.
Publicado: (2015)

Enhancement of solubility of poorly water soluble anti hypertensive drug by nanosizing approach
por: Thakar, Divyesh, et al.
Publicado: (2012)

Effects of Polymers on the Drug Solubility and Dissolution Enhancement of Poorly Water-Soluble Rivaroxaban
por: Choi, Min-Jong, et al.
Publicado: (2022)

The Self-Assembly Phenomenon of Poloxamers and Its Effect on the Dissolution of a Poorly Soluble Drug from Solid Dispersions Obtained by Solvent Methods
por: Szafraniec, Joanna, et al.
Publicado: (2019)

Development of orally disintegrating tablets containing solid dispersion of a poorly soluble drug for enhanced dissolution: In-vitro optimization/in-vivo evaluation
por: Fouad, Shahinaze A., et al.
Publicado: (2020)

Nanocrystals of Poorly Soluble Drugs: Drug Bioavailability and Physicochemical Stability
por: Gigliobianco, Maria Rosa, et al.
Publicado: (2018)

Effect of Cyclodextrin Types and Co-Solvent on Solubility of a Poorly Water Soluble Drug
por: Charumanee, Suporn, et al.
Publicado: (2016)

Multicomponent cyclodextrin system for improvement of solubility and dissolution rate of poorly water soluble drug()
por: Patel, Mayank, et al.
Publicado: (2019)

Revealing facts behind spray dried solid dispersion technology used for solubility enhancement
por: Patel, Bhavesh B., et al.
Publicado: (2015)

Pulmonary Drug Delivery of Antimicrobials and Anticancer Drugs Using Solid Dispersions
por: Al-Obaidi, Hisham, et al.
Publicado: (2021)

Functionalized Liposome and Albumin-Based Systems as Carriers for Poorly Water-Soluble Anticancer Drugs: An Updated Review
por: Teixeira, Sofia, et al.
Publicado: (2022)

Investigation of Crystallization and Salt Formation of Poorly Water-Soluble Telmisartan for Enhanced Solubility
por: Park, Chulhun, et al.
Publicado: (2019)

Formulation of Orally Disintegrating Films as an Amorphous Solid Solution of a Poorly Water-Soluble Drug
por: Panraksa, Pattaraporn, et al.
Publicado: (2020)

Polymorph Impact on the Bioavailability and Stability of Poorly Soluble Drugs
por: Censi, Roberta, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_p4oms5irg5gia8ldvbfei9c1s7