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Engineering the Enantioselectivity of Yeast Old Yellow Enzyme OYE2y in Asymmetric Reduction of (E/Z)-Citral to (R)-Citronellal

The members of the Old Yellow Enzyme (OYE) family are capable of catalyzing the asymmetric reduction of (E/Z)-citral to (R)-citronellal—a key intermediate in the synthesis of L-menthol. The applications of OYE-mediated biotransformation are usually hampered by its insufficient enantioselectivity and...

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Detalles Bibliográficos
Autores principales: Ying, Xiangxian, Yu, Shihua, Huang, Meijuan, Wei, Ran, Meng, Shumin, Cheng, Feng, Yu, Meilan, Ying, Meirong, Zhao, Man, Wang, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470962/
https://www.ncbi.nlm.nih.gov/pubmed/30889828
http://dx.doi.org/10.3390/molecules24061057