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Sulfide (Na(2)S) and Polysulfide (Na(2)S(2)) Interacting with Doxycycline Produce/Scavenge Superoxide and Hydroxyl Radicals and Induce/Inhibit DNA Cleavage
Doxycycline (DOXY) is an antibiotic routinely prescribed in human and veterinary medicine for antibacterial treatment, but it has also numerous side effects that include oxidative stress, inflammation, cancer or hypoxia-induced injury. Endogenously produced hydrogen sulfide (H(2)S) and polysulfides...
Autores principales: | Misak, Anton, Kurakova, Lucia, Goffa, Eduard, Brezova, Vlasta, Grman, Marian, Ondriasova, Elena, Chovanec, Miroslav, Ondrias, Karol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470963/ https://www.ncbi.nlm.nih.gov/pubmed/30909480 http://dx.doi.org/10.3390/molecules24061148 |
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