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ER Stress is Involved in Epithelial-To-Mesenchymal Transition of Alveolar Epithelial Cells Exposed to a Hypoxic Microenvironment

Background: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal interstitial lung disease of unknown origin. Alveolar epithelial cells (AECs) play an important role in the fibrotic process as they undergo sustained endoplasmic reticulum (ER) stress, and may acquire a mesenchymal...

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Detalles Bibliográficos
Autores principales: Delbrel, Eva, Uzunhan, Yurdagül, Soumare, Abdoulaye, Gille, Thomas, Marchant, Dominique, Planès, Carole, Boncoeur, Emilie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470993/
https://www.ncbi.nlm.nih.gov/pubmed/30875855
http://dx.doi.org/10.3390/ijms20061299