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Upregulated Autophagy in Calcific Aortic Valve Stenosis Confers Protection of Valvular Interstitial Cells

Autophagy serves as a cell survival mechanism which becomes dysregulated under pathological conditions and aging. Aortic valve thickening and calcification causing left ventricular outflow obstruction is known as calcific aortic valve stenosis (CAVS). CAVS is a chronic and progressive disease which...

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Detalles Bibliográficos
Autores principales: Carracedo, Miguel, Persson, Oscar, Saliba-Gustafsson, Peter, Artiach, Gonzalo, Ehrenborg, Ewa, Eriksson, Per, Franco-Cereceda, Anders, Bäck, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471010/
https://www.ncbi.nlm.nih.gov/pubmed/30934548
http://dx.doi.org/10.3390/ijms20061486