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Upregulated Autophagy in Calcific Aortic Valve Stenosis Confers Protection of Valvular Interstitial Cells
Autophagy serves as a cell survival mechanism which becomes dysregulated under pathological conditions and aging. Aortic valve thickening and calcification causing left ventricular outflow obstruction is known as calcific aortic valve stenosis (CAVS). CAVS is a chronic and progressive disease which...
Autores principales: | Carracedo, Miguel, Persson, Oscar, Saliba-Gustafsson, Peter, Artiach, Gonzalo, Ehrenborg, Ewa, Eriksson, Per, Franco-Cereceda, Anders, Bäck, Magnus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471010/ https://www.ncbi.nlm.nih.gov/pubmed/30934548 http://dx.doi.org/10.3390/ijms20061486 |
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