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Oxymatrine-mediated maturation of dendritic cells leads to activation of FOXP3(+)/CD(4)(+) Treg cells and reversal of cisplatin-resistance in lung cancer cells

The dendritic cell (DC)-regulatory T (Treg) system serves a leading role in the immunosuppression of the tumor microenvironment, which is not conducive to radiotherapy and chemotherapy treatment for lung cancer. The present study aimed to investigate the effect of oxymatrine (OMT) on the DC-Treg sys...

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Detalles Bibliográficos
Autores principales: Liu, Hui, Zou, Manman, Li, Pei, Wang, Haifeng, Lin, Xijun, Ye, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471056/
https://www.ncbi.nlm.nih.gov/pubmed/30896871
http://dx.doi.org/10.3892/mmr.2019.10064