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Evaluation of a Methylcellulose and Hyaluronic Acid Hydrogel as a Vehicle for Rectal Delivery of Biologics

Biologics have changed the management of Inflammatory Bowel Disease (IBD), but there are concerns regarding unexpected systemic toxicity and loss of therapeutic response following administration by injection. Local delivery of biologics directly to the inflamed mucosa via rectal enema administration...

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Detalles Bibliográficos
Autores principales:	Aprodu, Andreea, Mantaj, Julia, Raimi-Abraham, Bahijja, Vllasaliu, Driton
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471061/ https://www.ncbi.nlm.nih.gov/pubmed/30893796 http://dx.doi.org/10.3390/pharmaceutics11030127

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