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Baicalein Suppresses Stem Cell-Like Characteristics in Radio- and Chemoresistant MDA-MB-231 Human Breast Cancer Cells through Up-Regulation of IFIT2

Resistance to both chemotherapy and radiation therapy is frequent in triple-negative breast cancer (TNBC) patients. We established treatment-resistant TNBC MDA-MB-231/IR cells by irradiating the parental MDA-MB-231 cells 25 times with 2 Gy irradiation and investigated the molecular mechanisms of acq...

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Detalles Bibliográficos
Autores principales: Koh, So Yae, Moon, Jeong Yong, Unno, Tatsuya, Cho, Somi Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471144/
https://www.ncbi.nlm.nih.gov/pubmed/30875792
http://dx.doi.org/10.3390/nu11030624

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