Cargando…

Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis

In this study, we demonstrate the fabrication of Y-doped bioactive glass (BG), which is proposed as a potential material for selective internal radiotherapy applications. Owing to its superior bioactivity and biodegradability, it overcomes the problem of yttrium aluminosilicate spheres that remain i...

Descripción completa

Detalles Bibliográficos
Autores principales: Hadush Tesfay, Abadi, Chou, Yu-Jen, Tan, Cheng-Yan, Fufa Bakare, Fetene, Tsou, Nien-Ti, Huang, E-Wen, Shih, Shao-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471150/
https://www.ncbi.nlm.nih.gov/pubmed/30934617
http://dx.doi.org/10.3390/ma12060986
_version_ 1783411962511622144
author Hadush Tesfay, Abadi
Chou, Yu-Jen
Tan, Cheng-Yan
Fufa Bakare, Fetene
Tsou, Nien-Ti
Huang, E-Wen
Shih, Shao-Ju
author_facet Hadush Tesfay, Abadi
Chou, Yu-Jen
Tan, Cheng-Yan
Fufa Bakare, Fetene
Tsou, Nien-Ti
Huang, E-Wen
Shih, Shao-Ju
author_sort Hadush Tesfay, Abadi
collection PubMed
description In this study, we demonstrate the fabrication of Y-doped bioactive glass (BG), which is proposed as a potential material for selective internal radiotherapy applications. Owing to its superior bioactivity and biodegradability, it overcomes the problem of yttrium aluminosilicate spheres that remain in the host body for a long duration after treatment. The preparation of Y-doped BG powders were carried out using a spray pyrolysis method. By using two different yttrium sources, we examine the change of the local distribution of yttrium concentration. In addition, characterizations of phase information, particle morphologies, surface areas, and bioactivity were also performed. The results show that both Y-doped BG powders are bioactive and the local Y distribution can be controlled.
format Online
Article
Text
id pubmed-6471150
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-64711502019-04-27 Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis Hadush Tesfay, Abadi Chou, Yu-Jen Tan, Cheng-Yan Fufa Bakare, Fetene Tsou, Nien-Ti Huang, E-Wen Shih, Shao-Ju Materials (Basel) Article In this study, we demonstrate the fabrication of Y-doped bioactive glass (BG), which is proposed as a potential material for selective internal radiotherapy applications. Owing to its superior bioactivity and biodegradability, it overcomes the problem of yttrium aluminosilicate spheres that remain in the host body for a long duration after treatment. The preparation of Y-doped BG powders were carried out using a spray pyrolysis method. By using two different yttrium sources, we examine the change of the local distribution of yttrium concentration. In addition, characterizations of phase information, particle morphologies, surface areas, and bioactivity were also performed. The results show that both Y-doped BG powders are bioactive and the local Y distribution can be controlled. MDPI 2019-03-25 /pmc/articles/PMC6471150/ /pubmed/30934617 http://dx.doi.org/10.3390/ma12060986 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hadush Tesfay, Abadi
Chou, Yu-Jen
Tan, Cheng-Yan
Fufa Bakare, Fetene
Tsou, Nien-Ti
Huang, E-Wen
Shih, Shao-Ju
Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis
title Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis
title_full Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis
title_fullStr Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis
title_full_unstemmed Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis
title_short Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis
title_sort control of dopant distribution in yttrium-doped bioactive glass for selective internal radiotherapy applications using spray pyrolysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471150/
https://www.ncbi.nlm.nih.gov/pubmed/30934617
http://dx.doi.org/10.3390/ma12060986
work_keys_str_mv AT hadushtesfayabadi controlofdopantdistributioninyttriumdopedbioactiveglassforselectiveinternalradiotherapyapplicationsusingspraypyrolysis
AT chouyujen controlofdopantdistributioninyttriumdopedbioactiveglassforselectiveinternalradiotherapyapplicationsusingspraypyrolysis
AT tanchengyan controlofdopantdistributioninyttriumdopedbioactiveglassforselectiveinternalradiotherapyapplicationsusingspraypyrolysis
AT fufabakarefetene controlofdopantdistributioninyttriumdopedbioactiveglassforselectiveinternalradiotherapyapplicationsusingspraypyrolysis
AT tsounienti controlofdopantdistributioninyttriumdopedbioactiveglassforselectiveinternalradiotherapyapplicationsusingspraypyrolysis
AT huangewen controlofdopantdistributioninyttriumdopedbioactiveglassforselectiveinternalradiotherapyapplicationsusingspraypyrolysis
AT shihshaoju controlofdopantdistributioninyttriumdopedbioactiveglassforselectiveinternalradiotherapyapplicationsusingspraypyrolysis