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Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis
In this study, we demonstrate the fabrication of Y-doped bioactive glass (BG), which is proposed as a potential material for selective internal radiotherapy applications. Owing to its superior bioactivity and biodegradability, it overcomes the problem of yttrium aluminosilicate spheres that remain i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471150/ https://www.ncbi.nlm.nih.gov/pubmed/30934617 http://dx.doi.org/10.3390/ma12060986 |
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author | Hadush Tesfay, Abadi Chou, Yu-Jen Tan, Cheng-Yan Fufa Bakare, Fetene Tsou, Nien-Ti Huang, E-Wen Shih, Shao-Ju |
author_facet | Hadush Tesfay, Abadi Chou, Yu-Jen Tan, Cheng-Yan Fufa Bakare, Fetene Tsou, Nien-Ti Huang, E-Wen Shih, Shao-Ju |
author_sort | Hadush Tesfay, Abadi |
collection | PubMed |
description | In this study, we demonstrate the fabrication of Y-doped bioactive glass (BG), which is proposed as a potential material for selective internal radiotherapy applications. Owing to its superior bioactivity and biodegradability, it overcomes the problem of yttrium aluminosilicate spheres that remain in the host body for a long duration after treatment. The preparation of Y-doped BG powders were carried out using a spray pyrolysis method. By using two different yttrium sources, we examine the change of the local distribution of yttrium concentration. In addition, characterizations of phase information, particle morphologies, surface areas, and bioactivity were also performed. The results show that both Y-doped BG powders are bioactive and the local Y distribution can be controlled. |
format | Online Article Text |
id | pubmed-6471150 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-64711502019-04-27 Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis Hadush Tesfay, Abadi Chou, Yu-Jen Tan, Cheng-Yan Fufa Bakare, Fetene Tsou, Nien-Ti Huang, E-Wen Shih, Shao-Ju Materials (Basel) Article In this study, we demonstrate the fabrication of Y-doped bioactive glass (BG), which is proposed as a potential material for selective internal radiotherapy applications. Owing to its superior bioactivity and biodegradability, it overcomes the problem of yttrium aluminosilicate spheres that remain in the host body for a long duration after treatment. The preparation of Y-doped BG powders were carried out using a spray pyrolysis method. By using two different yttrium sources, we examine the change of the local distribution of yttrium concentration. In addition, characterizations of phase information, particle morphologies, surface areas, and bioactivity were also performed. The results show that both Y-doped BG powders are bioactive and the local Y distribution can be controlled. MDPI 2019-03-25 /pmc/articles/PMC6471150/ /pubmed/30934617 http://dx.doi.org/10.3390/ma12060986 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Hadush Tesfay, Abadi Chou, Yu-Jen Tan, Cheng-Yan Fufa Bakare, Fetene Tsou, Nien-Ti Huang, E-Wen Shih, Shao-Ju Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis |
title | Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis |
title_full | Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis |
title_fullStr | Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis |
title_full_unstemmed | Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis |
title_short | Control of Dopant Distribution in Yttrium-Doped Bioactive Glass for Selective Internal Radiotherapy Applications Using Spray Pyrolysis |
title_sort | control of dopant distribution in yttrium-doped bioactive glass for selective internal radiotherapy applications using spray pyrolysis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471150/ https://www.ncbi.nlm.nih.gov/pubmed/30934617 http://dx.doi.org/10.3390/ma12060986 |
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