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The Role of 3′ to 5′ Reverse RNA Polymerization in tRNA Fidelity and Repair

The tRNA(His) guanylyltransferase (Thg1) superfamily includes enzymes that are found in all three domains of life that all share the common ability to catalyze the 3′ to 5′ synthesis of nucleic acids. This catalytic activity, which is the reverse of all other known DNA and RNA polymerases, makes thi...

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Detalles Bibliográficos
Autores principales:	Chen, Allan W., Jayasinghe, Malithi I., Chung, Christina Z., Rao, Bhalchandra S., Kenana, Rosan, Heinemann, Ilka U., Jackman, Jane E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471195/ https://www.ncbi.nlm.nih.gov/pubmed/30917604 http://dx.doi.org/10.3390/genes10030250

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