Exploring Bioequivalence of Dexketoprofen Trometamol Drug Products with the Gastrointestinal Simulator (GIS) and Precipitation Pathways Analyses

The present work aimed to explain the differences in oral performance in fasted humans who were categorized into groups based on the three different drug product formulations of dexketoprofen trometamol (DKT) salt—Using a combination of in vitro techniques and pharmacokinetic analysis. The non-bioeq...

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Detalles Bibliográficos
Autores principales: Bermejo, Marival, Kuminek, Gislaine, Al-Gousous, Jozef, Ruiz-Picazo, Alejandro, Tsume, Yasuhiro, Garcia-Arieta, Alfredo, González-Alvarez, Isabel, Hens, Bart, Mudie, Deanna, Amidon, Gregory E., Rodriguez-Hornedo, Nair, Amidon, Gordon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471271/
https://www.ncbi.nlm.nih.gov/pubmed/30884755
http://dx.doi.org/10.3390/pharmaceutics11030122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471271/
https://www.ncbi.nlm.nih.gov/pubmed/30884755
http://dx.doi.org/10.3390/pharmaceutics11030122

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