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Defining Processing Times for Accelerator Produced (225)Ac and Other Isotopes from Proton Irradiated Thorium

During the purification of radioisotopes, decay periods or time dependent purification steps may be required to achieve a certain level of radiopurity in the final product. Actinum-225 (Ac-225), Silver-111 (Ag-111), Astatine-211 (At-211), Ruthenium-105 (Ru-105), and Rhodium-105 (Rh-105) are produced...

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Autores principales: Fitzsimmons, Jonathan, Griswold, Justin, Medvedev, Dmitri, Cutler, Cathy S., Mausner, Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471325/
https://www.ncbi.nlm.nih.gov/pubmed/30897722
http://dx.doi.org/10.3390/molecules24061095
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author Fitzsimmons, Jonathan
Griswold, Justin
Medvedev, Dmitri
Cutler, Cathy S.
Mausner, Leonard
author_facet Fitzsimmons, Jonathan
Griswold, Justin
Medvedev, Dmitri
Cutler, Cathy S.
Mausner, Leonard
author_sort Fitzsimmons, Jonathan
collection PubMed
description During the purification of radioisotopes, decay periods or time dependent purification steps may be required to achieve a certain level of radiopurity in the final product. Actinum-225 (Ac-225), Silver-111 (Ag-111), Astatine-211 (At-211), Ruthenium-105 (Ru-105), and Rhodium-105 (Rh-105) are produced in a high energy proton irradiated thorium target. Experimentally measured cross sections, along with MCNP6-generated cross sections, were used to determine the quantities of Ac-225, Ag-111, At-211, Ru-105, Rh-105, and other co-produced radioactive impurities produced in a proton irradiated thorium target at Brookhaven Linac Isotope Producer (BLIP). Ac-225 and Ag-111 can be produced with high radiopurity by the proton irradiation of a thorium target at BLIP.
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spelling pubmed-64713252019-04-26 Defining Processing Times for Accelerator Produced (225)Ac and Other Isotopes from Proton Irradiated Thorium Fitzsimmons, Jonathan Griswold, Justin Medvedev, Dmitri Cutler, Cathy S. Mausner, Leonard Molecules Article During the purification of radioisotopes, decay periods or time dependent purification steps may be required to achieve a certain level of radiopurity in the final product. Actinum-225 (Ac-225), Silver-111 (Ag-111), Astatine-211 (At-211), Ruthenium-105 (Ru-105), and Rhodium-105 (Rh-105) are produced in a high energy proton irradiated thorium target. Experimentally measured cross sections, along with MCNP6-generated cross sections, were used to determine the quantities of Ac-225, Ag-111, At-211, Ru-105, Rh-105, and other co-produced radioactive impurities produced in a proton irradiated thorium target at Brookhaven Linac Isotope Producer (BLIP). Ac-225 and Ag-111 can be produced with high radiopurity by the proton irradiation of a thorium target at BLIP. MDPI 2019-03-20 /pmc/articles/PMC6471325/ /pubmed/30897722 http://dx.doi.org/10.3390/molecules24061095 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fitzsimmons, Jonathan
Griswold, Justin
Medvedev, Dmitri
Cutler, Cathy S.
Mausner, Leonard
Defining Processing Times for Accelerator Produced (225)Ac and Other Isotopes from Proton Irradiated Thorium
title Defining Processing Times for Accelerator Produced (225)Ac and Other Isotopes from Proton Irradiated Thorium
title_full Defining Processing Times for Accelerator Produced (225)Ac and Other Isotopes from Proton Irradiated Thorium
title_fullStr Defining Processing Times for Accelerator Produced (225)Ac and Other Isotopes from Proton Irradiated Thorium
title_full_unstemmed Defining Processing Times for Accelerator Produced (225)Ac and Other Isotopes from Proton Irradiated Thorium
title_short Defining Processing Times for Accelerator Produced (225)Ac and Other Isotopes from Proton Irradiated Thorium
title_sort defining processing times for accelerator produced (225)ac and other isotopes from proton irradiated thorium
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471325/
https://www.ncbi.nlm.nih.gov/pubmed/30897722
http://dx.doi.org/10.3390/molecules24061095
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