Cargando…
Two-step Synthesis of Solasodine Pivalate from Diosgenin Pivalate
A two-step synthesis of solasodine pivalate from diosgenin pivalate is described. The key transformation involves the reaction of diosgenin pivalate with benzyl carbamate (CbzNH(2)) promoted by TMSOTf. During the reaction the F-ring of the spiroketal moiety opens up with a simultaneous introduction...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471385/ https://www.ncbi.nlm.nih.gov/pubmed/30901960 http://dx.doi.org/10.3390/molecules24061132 |