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Effect of A22 on the Conformation of Bacterial Actin MreB
The mechanism of the antibiotic molecule A22 is yet to be clearly understood. In a previous study, we carried out molecular dynamics simulations of a monomer of the bacterial actin-like MreB in complex with different nucleotides and A22, and suggested that A22 impedes the release of P(i) from the ac...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471442/ https://www.ncbi.nlm.nih.gov/pubmed/30875875 http://dx.doi.org/10.3390/ijms20061304 |