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Neuronanomedicine: An Up-to-Date Overview

The field of neuronanomedicine has recently emerged as the bridge between neurological sciences and nanotechnology. The possibilities of this novel perspective are promising for the diagnosis and treatment strategies of severe central nervous system disorders. Therefore, the development of nano-vehi...

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Detalles Bibliográficos
Autores principales: Teleanu, Daniel Mihai, Chircov, Cristina, Grumezescu, Alexandru Mihai, Teleanu, Raluca Ioana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471564/
https://www.ncbi.nlm.nih.gov/pubmed/30813646
http://dx.doi.org/10.3390/pharmaceutics11030101
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author Teleanu, Daniel Mihai
Chircov, Cristina
Grumezescu, Alexandru Mihai
Teleanu, Raluca Ioana
author_facet Teleanu, Daniel Mihai
Chircov, Cristina
Grumezescu, Alexandru Mihai
Teleanu, Raluca Ioana
author_sort Teleanu, Daniel Mihai
collection PubMed
description The field of neuronanomedicine has recently emerged as the bridge between neurological sciences and nanotechnology. The possibilities of this novel perspective are promising for the diagnosis and treatment strategies of severe central nervous system disorders. Therefore, the development of nano-vehicles capable of permeating the blood–brain barrier (BBB) and reaching the brain parenchyma may lead to breakthrough therapies that could improve life expectancy and quality of the patients diagnosed with brain disorders. The aim of this review is to summarize the recently developed organic, inorganic, and biological nanocarriers that could be used for the delivery of imaging and therapeutic agents to the brain, as well as the latest studies on the use of nanomaterials in brain cancer, neurodegenerative diseases, and stroke. Additionally, the main challenges and limitations associated with the use of these nanocarriers are briefly presented.
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spelling pubmed-64715642019-04-27 Neuronanomedicine: An Up-to-Date Overview Teleanu, Daniel Mihai Chircov, Cristina Grumezescu, Alexandru Mihai Teleanu, Raluca Ioana Pharmaceutics Review The field of neuronanomedicine has recently emerged as the bridge between neurological sciences and nanotechnology. The possibilities of this novel perspective are promising for the diagnosis and treatment strategies of severe central nervous system disorders. Therefore, the development of nano-vehicles capable of permeating the blood–brain barrier (BBB) and reaching the brain parenchyma may lead to breakthrough therapies that could improve life expectancy and quality of the patients diagnosed with brain disorders. The aim of this review is to summarize the recently developed organic, inorganic, and biological nanocarriers that could be used for the delivery of imaging and therapeutic agents to the brain, as well as the latest studies on the use of nanomaterials in brain cancer, neurodegenerative diseases, and stroke. Additionally, the main challenges and limitations associated with the use of these nanocarriers are briefly presented. MDPI 2019-02-26 /pmc/articles/PMC6471564/ /pubmed/30813646 http://dx.doi.org/10.3390/pharmaceutics11030101 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Teleanu, Daniel Mihai
Chircov, Cristina
Grumezescu, Alexandru Mihai
Teleanu, Raluca Ioana
Neuronanomedicine: An Up-to-Date Overview
title Neuronanomedicine: An Up-to-Date Overview
title_full Neuronanomedicine: An Up-to-Date Overview
title_fullStr Neuronanomedicine: An Up-to-Date Overview
title_full_unstemmed Neuronanomedicine: An Up-to-Date Overview
title_short Neuronanomedicine: An Up-to-Date Overview
title_sort neuronanomedicine: an up-to-date overview
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471564/
https://www.ncbi.nlm.nih.gov/pubmed/30813646
http://dx.doi.org/10.3390/pharmaceutics11030101
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