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Neuronanomedicine: An Up-to-Date Overview
The field of neuronanomedicine has recently emerged as the bridge between neurological sciences and nanotechnology. The possibilities of this novel perspective are promising for the diagnosis and treatment strategies of severe central nervous system disorders. Therefore, the development of nano-vehi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471564/ https://www.ncbi.nlm.nih.gov/pubmed/30813646 http://dx.doi.org/10.3390/pharmaceutics11030101 |
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author | Teleanu, Daniel Mihai Chircov, Cristina Grumezescu, Alexandru Mihai Teleanu, Raluca Ioana |
author_facet | Teleanu, Daniel Mihai Chircov, Cristina Grumezescu, Alexandru Mihai Teleanu, Raluca Ioana |
author_sort | Teleanu, Daniel Mihai |
collection | PubMed |
description | The field of neuronanomedicine has recently emerged as the bridge between neurological sciences and nanotechnology. The possibilities of this novel perspective are promising for the diagnosis and treatment strategies of severe central nervous system disorders. Therefore, the development of nano-vehicles capable of permeating the blood–brain barrier (BBB) and reaching the brain parenchyma may lead to breakthrough therapies that could improve life expectancy and quality of the patients diagnosed with brain disorders. The aim of this review is to summarize the recently developed organic, inorganic, and biological nanocarriers that could be used for the delivery of imaging and therapeutic agents to the brain, as well as the latest studies on the use of nanomaterials in brain cancer, neurodegenerative diseases, and stroke. Additionally, the main challenges and limitations associated with the use of these nanocarriers are briefly presented. |
format | Online Article Text |
id | pubmed-6471564 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-64715642019-04-27 Neuronanomedicine: An Up-to-Date Overview Teleanu, Daniel Mihai Chircov, Cristina Grumezescu, Alexandru Mihai Teleanu, Raluca Ioana Pharmaceutics Review The field of neuronanomedicine has recently emerged as the bridge between neurological sciences and nanotechnology. The possibilities of this novel perspective are promising for the diagnosis and treatment strategies of severe central nervous system disorders. Therefore, the development of nano-vehicles capable of permeating the blood–brain barrier (BBB) and reaching the brain parenchyma may lead to breakthrough therapies that could improve life expectancy and quality of the patients diagnosed with brain disorders. The aim of this review is to summarize the recently developed organic, inorganic, and biological nanocarriers that could be used for the delivery of imaging and therapeutic agents to the brain, as well as the latest studies on the use of nanomaterials in brain cancer, neurodegenerative diseases, and stroke. Additionally, the main challenges and limitations associated with the use of these nanocarriers are briefly presented. MDPI 2019-02-26 /pmc/articles/PMC6471564/ /pubmed/30813646 http://dx.doi.org/10.3390/pharmaceutics11030101 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Teleanu, Daniel Mihai Chircov, Cristina Grumezescu, Alexandru Mihai Teleanu, Raluca Ioana Neuronanomedicine: An Up-to-Date Overview |
title | Neuronanomedicine: An Up-to-Date Overview |
title_full | Neuronanomedicine: An Up-to-Date Overview |
title_fullStr | Neuronanomedicine: An Up-to-Date Overview |
title_full_unstemmed | Neuronanomedicine: An Up-to-Date Overview |
title_short | Neuronanomedicine: An Up-to-Date Overview |
title_sort | neuronanomedicine: an up-to-date overview |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471564/ https://www.ncbi.nlm.nih.gov/pubmed/30813646 http://dx.doi.org/10.3390/pharmaceutics11030101 |
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