Progression of Cystic Fibrosis Lung Disease from Childhood to Adulthood: Neutrophils, Neutrophil Extracellular Trap (NET) Formation, and NET Degradation

Genetic defects in cystic fibrosis (CF) transmembrane conductance regulator (CFTR) gene cause CF. Infants with CFTR mutations show a peribronchial neutrophil infiltration prior to the establishment of infection in their lung. The inflammatory response progressively increases in children that include...

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Detalles Bibliográficos
Autores principales: Khan, Meraj A., Ali, Zubair Sabz, Sweezey, Neil, Grasemann, Hartmut, Palaniyar, Nades
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471578/
https://www.ncbi.nlm.nih.gov/pubmed/30813645
http://dx.doi.org/10.3390/genes10030183

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